Annexon, Inc. (ANNX) vs 4D Molecular Therapeutics, Inc. (FDMT)
A side-by-side comparison of Annexon, Inc. and 4D Molecular Therapeutics, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
ANNX
Annexon, Inc.
$4.12HealthcareDelayed quote: Oct 6, 2026, 10:05 AM EDT
FDMT
4D Molecular Therapeutics, Inc.
$12.43HealthcareDelayed quote: Oct 6, 2026, 10:05 AM EDT
Total return — ANNX vs FDMT
growth of $100 · dividends reinvested · last 6yANNX -83.1% (-25.6%/yr)FDMT -68.1% (-17.3%/yr)FDMT compounded faster over this window
ANNX FDMT
ANNX vs FDMT: by the numbers
- •ANNX is the larger company ($674M vs $650M market cap).
- •Both run net losses; ANNX's is the smaller (0.00% vs -194.74% net margin).
Metrics side by side
Valuation
| Metric | ANNX | FDMT |
|---|---|---|
| P/S ratio | N/A | 7.06 |
| P/B ratio | 3.62 | 1.59 |
Profitability
| Metric | ANNX | FDMT |
|---|---|---|
| Gross margin | 0.00% | 91.05% |
| Operating margin | 0.00% | -187.24% |
| Net margin | 0.00% | -194.74% |
| ROE | -108.93% | -43.95% |
| ROIC | -101.43% | -44.30% |
Growth (annualized)
| Metric | ANNX | FDMT |
|---|---|---|
| Revenue CAGR (5Y) | N/A | 31.93% |
| Total return CAGR (5Y) | -26.29% | -13.08% |
Frequently asked
- How have ANNX and FDMT total returns compared?
- Over the past 5 years, ANNX delivered -26.29% and FDMT delivered -13.08% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Annexon ROE4D Molecular Therapeutics ROEAnnexon operating margin4D Molecular Therapeutics operating marginAnnexon revenue growth4D Molecular Therapeutics revenue growthAnnexon free cash flow4D Molecular Therapeutics free cash flow
Annexon & 4D Molecular Therapeutics appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.