Annexon, Inc. (ANNX) vs Avalo Therapeutics, Inc. (AVTX)
A side-by-side comparison of Annexon, Inc. and Avalo Therapeutics, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
ANNX
Annexon, Inc.
$4.12HealthcareDelayed quote: Oct 6, 2026, 12:55 PM EDT
AVTX
Avalo Therapeutics, Inc.
$13.37HealthcareDelayed quote: Oct 6, 2026, 12:55 PM EDT
Total return — ANNX vs AVTX
growth of $100 · dividends reinvested · last 6yANNX -76.4% (-21.4%/yr)AVTX -99.8% (-65.3%/yr)ANNX compounded faster over this window
Log scale — wide-divergence pair
ANNX AVTX
ANNX vs AVTX: by the numbers
- •AVTX is the larger company ($703M vs $674M market cap).
- •Both run net losses; ANNX's is the smaller (0.00% vs -170055.93% net margin).
Metrics side by side
Valuation
| Metric | ANNX | AVTX |
|---|---|---|
| P/S ratio | N/A | 11910.30 |
| P/B ratio | 3.62 | 1.57 |
Profitability
| Metric | ANNX | AVTX |
|---|---|---|
| Gross margin | 0.00% | 100.00% |
| Operating margin | 0.00% | -123601.69% |
| Net margin | 0.00% | -170055.93% |
| ROE | -108.93% | -22.36% |
| ROIC | -101.43% | -19.45% |
Growth (annualized)
| Metric | ANNX | AVTX |
|---|---|---|
| Revenue CAGR (5Y) | N/A | -60.88% |
| Total return CAGR (5Y) | -26.29% | -70.04% |
Frequently asked
- How have ANNX and AVTX total returns compared?
- Over the past 5 years, ANNX delivered -26.29% and AVTX delivered -70.04% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.