Is ANIP or STOK more profitable?

ANIP runs the higher net margin — ANIP at 10.82% versus STOK at -753.60%.

How have ANIP and STOK total returns compared?

Over the past 5 years, ANIP delivered 16.86% and STOK delivered -0.24% annualized total return. Past performance doesn't predict future results.

ANI Pharmaceuticals, Inc. (ANIP) vs Stoke Therapeutics, Inc. (STOK)

A side-by-side comparison of ANI Pharmaceuticals, Inc. and Stoke Therapeutics, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

ANIP

ANI Pharmaceuticals, Inc.

$1.62B

$71.45HealthcareDelayed quote: Oct 6, 2026, 3:10 PM EDT

STOK

Stoke Therapeutics, Inc.

$1.57B

$24.28HealthcareDelayed quote: Oct 6, 2026, 3:05 PM EDT

Total return — ANIP vs STOK

growth of $100 · dividends reinvested · last 7y

ANIP -2.4% (-0.4%/yr)STOK -1.0% (-0.1%/yr)STOK compounded faster over this window

ANIP STOK

ANIP vs STOK: by the numbers

•ANIP is the larger company ($1.62B vs $1.57B market cap).
•ANIP is profitable (10.82% net margin) while STOK runs a net loss (-753.60%).

Metrics side by side

Valuation

Metric	ANIP	STOK
P/E ratio	15.43	N/A
Forward P/E	7.70	N/A
P/S ratio	1.66	56.79
P/B ratio	2.72	4.53
EV / EBITDA	6.76	N/A

Profitability

Metric	ANIP	STOK
Gross margin	51.01%	100.00%
Operating margin	15.35%	-11.16%
Net margin	10.82%	-753.60%
ROE	17.72%	-60.17%
ROIC	9.26%	-63.12%

Growth (annualized)

Metric	ANIP	STOK
Revenue CAGR (5Y)	35.61%	N/A
Total return CAGR (5Y)	16.86%	-0.24%

Frequently asked

Is ANIP or STOK more profitable?: ANIP runs the higher net margin — ANIP at 10.82% versus STOK at -753.60%.
How have ANIP and STOK total returns compared?: Over the past 5 years, ANIP delivered 16.86% and STOK delivered -0.24% annualized total return. Past performance doesn't predict future results.

Go deeper

Full ANIP analysis Full STOK analysis Interactive comparison tool

Dig into the metrics

ANI Pharmaceuticals P/E ratio ANI Pharmaceuticals ROE Stoke Therapeutics ROE ANI Pharmaceuticals operating margin Stoke Therapeutics operating margin ANI Pharmaceuticals revenue growth Stoke Therapeutics revenue growth ANI Pharmaceuticals free cash flow Stoke Therapeutics free cash flow

ANI Pharmaceuticals & Stoke Therapeutics appear in these rankings

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Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.