Which has the lower trailing P/E, ANAB or OMER?

ANAB has the lower trailing P/E: ANAB trades at 8.97 and OMER at 10.87. P/E is one valuation measure and does not by itself establish which business is cheaper.

Which has grown faster, ANAB or OMER?

Over the past five years, ANAB grew revenue faster — ANAB at a 18.60% CAGR versus OMER at 0.90%.

Is ANAB or OMER more profitable?

OMER runs the higher net margin — ANAB at 82.37% versus OMER at 324.88%.

How have ANAB and OMER total returns compared?

Over the past 5 years, ANAB delivered 21.54% and OMER delivered 21.70% annualized total return. Past performance doesn't predict future results.

AnaptysBio, Inc. (ANAB) vs Omeros Corporation (OMER)

A side-by-side comparison of AnaptysBio, Inc. and Omeros Corporation across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

ANAB

AnaptysBio, Inc.

$1.43B

$48.19HealthcareDelayed quote: Oct 6, 2026, 12:30 PM EDT

OMER

Omeros Corporation

$1.35B

$18.69HealthcareDelayed quote: Oct 6, 2026, 12:25 PM EDT

Total return — ANAB vs OMER

growth of $100 · dividends reinvested · last 10y

ANAB +334.2% (+15.8%/yr)OMER +105.2% (+7.5%/yr)ANAB compounded faster over this window

ANAB OMER

ANAB vs OMER: by the numbers

•ANAB is the larger company ($1.43B vs $1.35B market cap).
•ANAB trades at the lower trailing earnings multiple (8.97 vs 10.87 P/E), one valuation lens rather than an overall verdict.
•OMER converts more revenue to profit (324.88% vs 82.37% net margin).
•ANAB grew revenue faster over the past five years (18.60% vs 0.90% CAGR).

Metrics side by side

Valuation

Metric	ANAB	OMER
P/E ratio	8.97	10.87
Forward P/E	N/A	20.62
P/S ratio	6.00	35.21
P/B ratio	134.80	N/A
EV / EBITDA	11.51	N/A
FCF yield	1.26%	N/A

Profitability

Metric	ANAB	OMER
Gross margin	98.97%	0.00%
Operating margin	20.42%	0.00%
Net margin	82.37%	324.88%
ROE	1849.06%	N/A
ROIC	47.55%	-32.06%

Growth (annualized)

Metric	ANAB	OMER
Revenue CAGR (5Y)	18.60%	0.90%
FCF CAGR (5Y)	27.41%	N/A
Total return CAGR (5Y)	21.54%	21.70%

Frequently asked

Which has the lower trailing P/E, ANAB or OMER?: ANAB has the lower trailing P/E: ANAB trades at 8.97 and OMER at 10.87. P/E is one valuation measure and does not by itself establish which business is cheaper.
Which has grown faster, ANAB or OMER?: Over the past five years, ANAB grew revenue faster — ANAB at a 18.60% CAGR versus OMER at 0.90%.
Is ANAB or OMER more profitable?: OMER runs the higher net margin — ANAB at 82.37% versus OMER at 324.88%.
How have ANAB and OMER total returns compared?: Over the past 5 years, ANAB delivered 21.54% and OMER delivered 21.70% annualized total return. Past performance doesn't predict future results.

Go deeper

Full ANAB analysis Full OMER analysis Interactive comparison tool

Dig into the metrics

AnaptysBio P/E ratio Omeros P/E ratio AnaptysBio ROE Omeros ROE AnaptysBio operating margin Omeros operating margin AnaptysBio revenue growth Omeros revenue growth AnaptysBio free cash flow Omeros free cash flow

AnaptysBio & Omeros appear in these rankings

Fastest Revenue Growth Stocks Highest ROE Stocks Highest ROIC Stocks Lowest P/E Ratio Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.