Amphastar Pharmaceuticals, Inc. (AMPH) vs Tyra Biosciences, Inc. (TYRA)
A side-by-side comparison of Amphastar Pharmaceuticals, Inc. and Tyra Biosciences, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
AMPH
Amphastar Pharmaceuticals, Inc.
$25.80HealthcareDelayed quote: Oct 6, 2026, 3:05 PM EDT
TYRA
Tyra Biosciences, Inc.
$20.18HealthcareDelayed quote: Oct 6, 2026, 3:05 PM EDT
Total return — AMPH vs TYRA
growth of $100 · dividends reinvested · last 5yAMPH +42.3% (+7.3%/yr)TYRA -19.5% (-4.2%/yr)AMPH compounded faster over this window
AMPH TYRA
AMPH vs TYRA: by the numbers
- •TYRA is the larger company ($1.20B vs $1.14B market cap).
- •AMPH is profitable (10.76% net margin) while TYRA runs a net loss (0.00%).
Metrics side by side
Valuation
| Metric | AMPH | TYRA |
|---|---|---|
| P/E ratio | 15.26 | N/A |
| Forward P/E | 8.68 | N/A |
| PEG ratio | 0.11 | N/A |
| P/S ratio | 1.56 | N/A |
| P/B ratio | 1.48 | 3.40 |
| EV / EBITDA | 8.93 | N/A |
| FCF yield | 13.44% | N/A |
Profitability
| Metric | AMPH | TYRA |
|---|---|---|
| Gross margin | 47.68% | 0.00% |
| Operating margin | 15.66% | 0.00% |
| Net margin | 10.76% | 0.00% |
| ROE | 10.23% | -42.01% |
| ROIC | 5.93% | -44.73% |
Growth (annualized)
| Metric | AMPH | TYRA |
|---|---|---|
| Revenue CAGR (5Y) | 13.71% | N/A |
| EPS CAGR (5Y) | 134.23% | N/A |
| FCF CAGR (5Y) | 23.90% | N/A |
| Total return CAGR (5Y) | 6.13% | 9.23% |
Frequently asked
- Is AMPH or TYRA more profitable?
- AMPH runs the higher net margin — AMPH at 10.76% versus TYRA at 0.00%.
- How have AMPH and TYRA total returns compared?
- Over the past 5 years, AMPH delivered 6.13% and TYRA delivered 9.23% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Amphastar Pharmaceuticals P/E ratioAmphastar Pharmaceuticals ROETyra Biosciences ROEAmphastar Pharmaceuticals operating marginTyra Biosciences operating marginAmphastar Pharmaceuticals revenue growthTyra Biosciences revenue growthAmphastar Pharmaceuticals free cash flowTyra Biosciences free cash flow
Amphastar Pharmaceuticals & Tyra Biosciences appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.