Which has grown faster, AMPH or NKTR?

Over the past five years, AMPH grew revenue faster — AMPH at a 13.71% CAGR versus NKTR at -12.34%.

Is AMPH or NKTR more profitable?

AMPH runs the higher net margin — AMPH at 10.76% versus NKTR at -287.84%.

How have AMPH and NKTR total returns compared?

Over the past 10 years, AMPH delivered 2.47% and NKTR delivered -16.49% annualized total return. Past performance doesn't predict future results.

Amphastar Pharmaceuticals, Inc. (AMPH) vs Nektar Therapeutics (NKTR)

A side-by-side comparison of Amphastar Pharmaceuticals, Inc. and Nektar Therapeutics across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

AMPH

Amphastar Pharmaceuticals, Inc.

$1.13B

$25.59HealthcareDelayed quote: Oct 6, 2026, 3:35 PM EDT

NKTR

Nektar Therapeutics

$1.14B

$39.57HealthcareDelayed quote: Oct 6, 2026, 3:35 PM EDT

Total return — AMPH vs NKTR

growth of $100 · dividends reinvested · last 10y

AMPH +32.8% (+2.9%/yr)NKTR -83.4% (-16.4%/yr)AMPH compounded faster over this window

Log scale — wide-divergence pair

AMPH NKTR

AMPH vs NKTR: by the numbers

•NKTR is the larger company ($1.14B vs $1.13B market cap).
•AMPH is profitable (10.76% net margin) while NKTR runs a net loss (-287.84%).
•AMPH grew revenue faster over the past five years (13.71% vs -12.34% CAGR).

Metrics side by side

Valuation

Metric	AMPH	NKTR
P/E ratio	15.14	N/A
Forward P/E	8.61	N/A
PEG ratio	0.11	N/A
P/S ratio	1.55	20.80
P/B ratio	1.47	1.26
EV / EBITDA	8.87	N/A
FCF yield	13.55%	N/A

Profitability

Metric	AMPH	NKTR
Gross margin	47.68%	99.36%
Operating margin	15.66%	-240.38%
Net margin	10.76%	-287.84%
ROE	10.23%	-17.40%
ROIC	5.93%	-12.53%

Growth (annualized)

Metric	AMPH	NKTR
Revenue CAGR (5Y)	13.71%	-12.34%
EPS CAGR (5Y)	134.23%	N/A
FCF CAGR (5Y)	23.90%	N/A
Total return CAGR (5Y)	6.13%	-30.33%

Frequently asked

Which has grown faster, AMPH or NKTR?: Over the past five years, AMPH grew revenue faster — AMPH at a 13.71% CAGR versus NKTR at -12.34%.
Is AMPH or NKTR more profitable?: AMPH runs the higher net margin — AMPH at 10.76% versus NKTR at -287.84%.
How have AMPH and NKTR total returns compared?: Over the past 10 years, AMPH delivered 2.47% and NKTR delivered -16.49% annualized total return. Past performance doesn't predict future results.

Go deeper

Full AMPH analysis Full NKTR analysis Interactive comparison tool

Dig into the metrics

Amphastar Pharmaceuticals P/E ratio Amphastar Pharmaceuticals ROE Nektar Therapeutics ROE Amphastar Pharmaceuticals operating margin Nektar Therapeutics operating margin Amphastar Pharmaceuticals revenue growth Nektar Therapeutics revenue growth Amphastar Pharmaceuticals free cash flow Nektar Therapeutics free cash flow

Amphastar Pharmaceuticals & Nektar Therapeutics appear in these rankings

Highest FCF Yield Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.