Amylyx Pharmaceuticals, Inc. (AMLX) vs IDEAYA Biosciences, Inc. (IDYA)

A side-by-side comparison of Amylyx Pharmaceuticals, Inc. and IDEAYA Biosciences, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

AMLX

Amylyx Pharmaceuticals, Inc.

$3.03B

$27.24HealthcareDelayed quote: Oct 6, 2026, 10:25 AM EDT

IDYA

IDEAYA Biosciences, Inc.

$3.49B

$36.67HealthcareDelayed quote: Oct 6, 2026, 10:25 AM EDT

Total return — AMLX vs IDYA

growth of $100 · dividends reinvested · last 5y

AMLX +53.7% (+9.0%/yr)IDYA +91.1% (+13.8%/yr)IDYA compounded faster over this window

AMLX IDYA

AMLX vs IDYA: by the numbers

•IDYA is the larger company ($3.49B vs $3.03B market cap).
•Both run net losses; AMLX's is the smaller (0.00% vs -74.75% net margin).

Metrics side by side

Valuation

Metric	AMLX	IDYA
P/S ratio	N/A	14.89
P/B ratio	12.66	2.91

Profitability

Metric	AMLX	IDYA
Gross margin	0.00%	-43.89%
Operating margin	0.00%	-72.84%
Net margin	0.00%	-74.75%
ROE	-63.59%	-14.60%
ROIC	-66.60%	-17.68%

Growth (annualized)

Metric	AMLX	IDYA
Revenue CAGR (5Y)	N/A	45.80%
Total return CAGR (5Y)	N/A	7.32%

Go deeper

Full AMLX analysis Full IDYA analysis Interactive comparison tool

Dig into the metrics

Amylyx Pharmaceuticals ROE IDEAYA Biosciences ROE Amylyx Pharmaceuticals operating margin IDEAYA Biosciences operating margin Amylyx Pharmaceuticals revenue growth IDEAYA Biosciences revenue growth Amylyx Pharmaceuticals free cash flow IDEAYA Biosciences free cash flow

Amylyx Pharmaceuticals & IDEAYA Biosciences appear in these rankings

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Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.