Amylyx Pharmaceuticals, Inc. (AMLX) vs Dyne Therapeutics, Inc. (DYN)

A side-by-side comparison of Amylyx Pharmaceuticals, Inc. and Dyne Therapeutics, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

Compare

Total return — AMLX vs DYN

growth of $100 · dividends reinvested · last 5y
AMLX +53.7% (+9.0%/yr)DYN +41.9% (+7.3%/yr)AMLX compounded faster over this window
0100200300400Start $1002023202420252026$154$142
AMLX DYN

AMLX vs DYN: by the numbers

  • •AMLX is the larger company ($3.08B vs $2.83B market cap).

Metrics side by side

Valuation

MetricAMLXDYN
P/B ratio12.864.03

Profitability

MetricAMLXDYN
Gross margin0.00%0.00%
Operating margin0.00%0.00%
Net margin0.00%0.00%
ROE-63.59%-73.97%
ROIC-66.60%-58.28%

Growth (annualized)

MetricAMLXDYN
Total return CAGR (5Y)N/A-0.38%

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.