Amgen Inc. (AMGN) vs Thermo Fisher Scientific Inc. (TMO)

A side-by-side comparison of Amgen Inc. and Thermo Fisher Scientific Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of September 10, 2026. Differences are shown without an overall score or investment verdict.

Compare

Total returnAMGN vs TMO

growth of $100 · dividends reinvested · last 10y
AMGN +245.1% (+13.2%/yr)TMO +314.9% (+15.3%/yr)TMO compounded faster over this window
100200300400Start $10020182020202220242026$345$415
AMGN TMO

AMGN vs TMO: by the numbers

  • TMO is the larger company ($226.62B vs $203.66B market cap).
  • AMGN trades at the lower trailing earnings multiple (23.45 vs 32.80 P/E), one valuation lens rather than an overall verdict.
  • AMGN converts more revenue to profit (22.93% vs 15.06% net margin).
  • AMGN grew revenue faster over the past five years (8.39% vs 5.00% CAGR).
  • AMGN pays the higher dividend yield (2.56% vs 0.30%).

Metrics side by side

Valuation

MetricAMGNTMO
P/E ratio23.4532.80
Forward P/E16.3524.29
P/S ratio5.344.89
P/B ratio17.424.30
EV / EBITDAN/A25.25
FCF yield5.00%3.23%

Profitability

MetricAMGNTMO
Gross margin72.65%40.37%
Operating margin33.18%17.69%
Net margin22.93%15.06%
ROE74.80%13.25%
ROIC14.22%7.44%

Dividends

MetricAMGNTMO
Dividend yield2.56%0.30%
Payout ratio60.91%9.68%

Growth (annualized)

MetricAMGNTMO
Revenue CAGR (5Y)8.39%5.00%
EPS CAGR (5Y)2.94%1.99%
FCF CAGR (5Y)-3.91%-1.83%
Total return CAGR (5Y)15.90%1.55%

Frequently asked

Which has the lower trailing P/E, AMGN or TMO?
AMGN has the lower trailing P/E: AMGN trades at 23.45 and TMO at 32.80. P/E is one valuation measure and does not by itself establish which business is cheaper.
Which has grown faster, AMGN or TMO?
Over the past five years, AMGN grew revenue faster — AMGN at a 8.39% CAGR versus TMO at 5.00%.
Does AMGN or TMO pay a bigger dividend?
AMGN yields 2.56% and TMO yields 0.30% based on trailing dividends and the latest price.
Is AMGN or TMO more profitable?
AMGN runs the higher net margin — AMGN at 22.93% versus TMO at 15.06%.
How have AMGN and TMO total returns compared?
Over the past 10 years, AMGN delivered 11.95% and TMO delivered 15.81% annualized total return. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified September 10, 2026.