Amgen Inc. (AMGN) vs Pfizer Inc. (PFE)

AMGN leads on 8 of 15 compared metrics, though PFE is the cheaper stock.

A side-by-side comparison of Amgen Inc. and Pfizer Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of June 13, 2026. The ● marks the stronger figure on each row (cheaper multiple, higher margin/return).

Total return — AMGN vs PFE

growth of $100 · last 30y
AMGN +2282.3%PFE +128.5%AMGN compounded faster
Log scale — wide-divergence pair
101001k10kStart $100200120062011201620212026$2,382$229
AMGN PFE

AMGN vs PFE: by the numbers

  • AMGN is the larger company ($191.70B vs $149.38B market cap).
  • PFE trades at the lower earnings multiple (20.01 vs 24.72 P/E).
  • AMGN converts more revenue to profit (20.95% vs 11.83% net margin).
  • PFE pays the higher dividend yield (6.56% vs 2.76%).

Which is better, AMGN or PFE?

Metric tally: AMGN 8 · PFE 7

It depends on what you're optimizing for:

ValuePFE(lower P/E)
IncomePFE(higher dividend yield)
QualityAMGN(higher ROIC)

Valuation

MetricAMGNPFE
P/E ratio24.7220.01
Forward P/E15.159.25
P/S ratio5.192.37
P/B ratio21.031.67
PEG ratio0.26
EV / EBITDA15.3212.72
FCF yield4.45%6.31%

Profitability

MetricAMGNPFE
Gross margin71.46%69.35%
Operating margin31.63%23.45%
Net margin20.95%11.83%
ROE84.87%8.31%
ROIC13.16%8.84%

Dividends

MetricAMGNPFE
Dividend yield2.76%6.56%
Payout ratio68.39%126.47%

Growth (annualized)

MetricAMGNPFE
Revenue CAGR (5Y)8.15%8.22%
EPS CAGR (5Y)2.94%-3.78%
FCF CAGR (5Y)-2.66%-3.79%
Total return CAGR (5Y)11.36%-3.33%

Frequently asked

Which is better, AMGN or PFE?
It depends on your goal. value: PFE (lower P/E); income: PFE (higher dividend yield); quality: AMGN (higher ROIC). Across all compared metrics, AMGN leads 8 to 7.
Is AMGN or PFE cheaper?
On trailing earnings, PFE is cheaper: AMGN trades at a 24.72 P/E and PFE at 20.01.
Which has grown faster, AMGN or PFE?
Over the past five years, PFE grew revenue faster — AMGN at a 8.15% CAGR versus PFE at 8.22%.
Does AMGN or PFE pay a bigger dividend?
AMGN yields 2.76% and PFE yields 6.56% based on trailing dividends and the latest price.
Is AMGN or PFE more profitable?
AMGN runs the higher net margin — AMGN at 20.95% versus PFE at 11.83%.
Which has been the better investment, AMGN or PFE?
Over the past 10-year, AMGN delivered the higher annualized total return — AMGN at 11.94% versus PFE at 2.13%. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified June 13, 2026.