Amgen Inc. (AMGN) vs Pfizer Inc. (PFE)
AMGN leads on 8 of 15 compared metrics, though PFE is the cheaper stock.
A side-by-side comparison of Amgen Inc. and Pfizer Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of June 13, 2026. The ● marks the stronger figure on each row (cheaper multiple, higher margin/return).
Total return — AMGN vs PFE
growth of $100 · last 30yAMGN +2282.3%PFE +128.5%AMGN compounded faster
Log scale — wide-divergence pair
AMGN PFE
AMGN vs PFE: by the numbers
- •AMGN is the larger company ($191.70B vs $149.38B market cap).
- •PFE trades at the lower earnings multiple (20.01 vs 24.72 P/E).
- •AMGN converts more revenue to profit (20.95% vs 11.83% net margin).
- •PFE pays the higher dividend yield (6.56% vs 2.76%).
Which is better, AMGN or PFE?
Metric tally: AMGN 8 · PFE 7It depends on what you're optimizing for:
ValuePFE(lower P/E)
IncomePFE(higher dividend yield)
QualityAMGN(higher ROIC)
Valuation
| Metric | AMGN | PFE |
|---|---|---|
| P/E ratio | 24.72 | 20.01● |
| Forward P/E | 15.15 | 9.25● |
| P/S ratio | 5.19 | 2.37● |
| P/B ratio | 21.03 | 1.67● |
| PEG ratio | 0.26 | — |
| EV / EBITDA | 15.32 | 12.72● |
| FCF yield | 4.45% | 6.31%● |
Profitability
| Metric | AMGN | PFE |
|---|---|---|
| Gross margin | 71.46%● | 69.35% |
| Operating margin | 31.63%● | 23.45% |
| Net margin | 20.95%● | 11.83% |
| ROE | 84.87%● | 8.31% |
| ROIC | 13.16%● | 8.84% |
Dividends
| Metric | AMGN | PFE |
|---|---|---|
| Dividend yield | 2.76% | 6.56%● |
| Payout ratio | 68.39% | 126.47% |
Growth (annualized)
| Metric | AMGN | PFE |
|---|---|---|
| Revenue CAGR (5Y) | 8.15% | 8.22% |
| EPS CAGR (5Y) | 2.94%● | -3.78% |
| FCF CAGR (5Y) | -2.66%● | -3.79% |
| Total return CAGR (5Y) | 11.36%● | -3.33% |
Frequently asked
- Which is better, AMGN or PFE?
- It depends on your goal. value: PFE (lower P/E); income: PFE (higher dividend yield); quality: AMGN (higher ROIC). Across all compared metrics, AMGN leads 8 to 7.
- Is AMGN or PFE cheaper?
- On trailing earnings, PFE is cheaper: AMGN trades at a 24.72 P/E and PFE at 20.01.
- Which has grown faster, AMGN or PFE?
- Over the past five years, PFE grew revenue faster — AMGN at a 8.15% CAGR versus PFE at 8.22%.
- Does AMGN or PFE pay a bigger dividend?
- AMGN yields 2.76% and PFE yields 6.56% based on trailing dividends and the latest price.
- Is AMGN or PFE more profitable?
- AMGN runs the higher net margin — AMGN at 20.95% versus PFE at 11.83%.
- Which has been the better investment, AMGN or PFE?
- Over the past 10-year, AMGN delivered the higher annualized total return — AMGN at 11.94% versus PFE at 2.13%. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Amgen P/E ratioPfizer P/E ratioAmgen dividend yieldPfizer dividend yieldAmgen ROEPfizer ROEAmgen operating marginPfizer operating marginAmgen revenue growthPfizer revenue growthAmgen free cash flowPfizer free cash flow
Amgen & Pfizer appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified June 13, 2026.