Which has the lower trailing P/E, AMGN or PFE?

AMGN has the lower trailing P/E: AMGN trades at 23.35 and PFE at 36.40. P/E is one valuation measure and does not by itself establish which business is cheaper.

Which has grown faster, AMGN or PFE?

Over the past five years, AMGN grew revenue faster — AMGN at a 8.39% CAGR versus PFE at 6.29%.

Does AMGN or PFE pay a bigger dividend?

AMGN yields 2.63% and PFE yields 6.20% based on trailing dividends and the latest price.

Is AMGN or PFE more profitable?

AMGN runs the higher net margin — AMGN at 22.93% versus PFE at 6.81%.

How have AMGN and PFE total returns compared?

Over the past 10 years, AMGN delivered 11.80% and PFE delivered 3.15% annualized total return. Past performance doesn't predict future results.

Amgen Inc. (AMGN) vs Pfizer Inc. (PFE)

A side-by-side comparison of Amgen Inc. and Pfizer Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of September 13, 2026. Differences are shown without an overall score or investment verdict.

AMGN

Amgen Inc.

$202.74B

$375.65HealthcareDelayed quote: Sep 15, 2026, 4:00 PM EDT

PFE

Pfizer Inc.

$157.02B

$27.55HealthcareDelayed quote: Sep 15, 2026, 4:02 PM EDT

Total return — AMGN vs PFE

growth of $100 · dividends reinvested · last 10y

AMGN +197.8% (+11.5%/yr)PFE +37.0% (+3.2%/yr)AMGN compounded faster over this window

AMGN PFE

AMGN vs PFE: by the numbers

•AMGN is the larger company ($202.74B vs $157.02B market cap).
•AMGN trades at the lower trailing earnings multiple (23.35 vs 36.40 P/E), one valuation lens rather than an overall verdict.
•AMGN converts more revenue to profit (22.93% vs 6.81% net margin).
•AMGN grew revenue faster over the past five years (8.39% vs 6.29% CAGR).
•PFE pays the higher dividend yield (6.20% vs 2.63%).

Metrics side by side

Valuation

Metric	AMGN	PFE
P/E ratio	23.35	36.40
Forward P/E	16.28	9.26
P/S ratio	5.32	2.47
P/B ratio	17.35	1.84
EV / EBITDA	N/A	10.11
FCF yield	5.02%	7.00%

Profitability

Metric	AMGN	PFE
Gross margin	72.65%	71.32%
Operating margin	33.18%	25.08%
Net margin	22.93%	6.81%
ROE	74.80%	5.09%
ROIC	14.22%	9.33%

Dividends

Metric	AMGN	PFE
Dividend yield	2.63%	6.20%
Payout ratio	61.78%	227.27%

Growth (annualized)

Metric	AMGN	PFE
Revenue CAGR (5Y)	8.39%	6.29%
EPS CAGR (5Y)	2.94%	-3.78%
FCF CAGR (5Y)	-3.91%	-3.11%
Total return CAGR (5Y)	15.58%	-4.53%

Frequently asked

Which has the lower trailing P/E, AMGN or PFE?: AMGN has the lower trailing P/E: AMGN trades at 23.35 and PFE at 36.40. P/E is one valuation measure and does not by itself establish which business is cheaper.
Which has grown faster, AMGN or PFE?: Over the past five years, AMGN grew revenue faster — AMGN at a 8.39% CAGR versus PFE at 6.29%.
Does AMGN or PFE pay a bigger dividend?: AMGN yields 2.63% and PFE yields 6.20% based on trailing dividends and the latest price.
Is AMGN or PFE more profitable?: AMGN runs the higher net margin — AMGN at 22.93% versus PFE at 6.81%.
How have AMGN and PFE total returns compared?: Over the past 10 years, AMGN delivered 11.80% and PFE delivered 3.15% annualized total return. Past performance doesn't predict future results.

Go deeper

Full AMGN analysis Full PFE analysis Interactive comparison tool

Dig into the metrics

Amgen P/E ratio Pfizer P/E ratio Amgen dividend yield Pfizer dividend yield Amgen ROE Pfizer ROE Amgen operating margin Pfizer operating margin Amgen revenue growth Pfizer revenue growth Amgen free cash flow Pfizer free cash flow

Amgen & Pfizer appear in these rankings

Highest Dividend Yield Stocks Highest ROE Stocks Highest Operating Margin Stocks Highest FCF Yield Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified September 13, 2026.