Amgen Inc. (AMGN) vs Novo Nordisk A/S (NVO)

A side-by-side comparison of Amgen Inc. and Novo Nordisk A/S across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of September 13, 2026. Differences are shown without an overall score or investment verdict.

Compare

Total returnAMGN vs NVO

growth of $100 · dividends reinvested · last 10y
AMGN +197.8% (+11.5%/yr)NVO +135.8% (+9.0%/yr)AMGN compounded faster over this window
200400600Start $10020182020202220242026$298$236
AMGN NVO

AMGN vs NVO: by the numbers

  • AMGN is the larger company ($202.74B vs $188.86B market cap).
  • NVO trades at the lower trailing earnings multiple (10.48 vs 23.35 P/E), one valuation lens rather than an overall verdict.
  • NVO converts more revenue to profit (35.33% vs 22.93% net margin).
  • NVO grew revenue faster over the past five years (19.76% vs 8.39% CAGR).
  • NVO pays the higher dividend yield (4.17% vs 2.63%).

Metrics side by side

Valuation

MetricAMGNNVO
P/E ratio23.3510.48
Forward P/E16.28N/A
P/S ratio5.323.70
P/B ratio17.355.60
EV / EBITDAN/A7.76
FCF yield5.02%3.94%

Profitability

MetricAMGNNVO
Gross margin72.65%80.64%
Operating margin33.18%43.10%
Net margin22.93%35.33%
ROE74.80%53.50%
ROIC14.22%30.21%

Dividends

MetricAMGNNVO
Dividend yield2.63%4.17%
Payout ratio61.78%44.27%

Growth (annualized)

MetricAMGNNVO
Revenue CAGR (5Y)8.39%19.76%
EPS CAGR (5Y)2.94%19.59%
FCF CAGR (5Y)-3.91%-1.45%
Total return CAGR (5Y)15.58%-0.65%

Frequently asked

Which has the lower trailing P/E, AMGN or NVO?
NVO has the lower trailing P/E: AMGN trades at 23.35 and NVO at 10.48. P/E is one valuation measure and does not by itself establish which business is cheaper.
Which has grown faster, AMGN or NVO?
Over the past five years, NVO grew revenue faster — AMGN at a 8.39% CAGR versus NVO at 19.76%.
Does AMGN or NVO pay a bigger dividend?
AMGN yields 2.63% and NVO yields 4.17% based on trailing dividends and the latest price.
Is AMGN or NVO more profitable?
NVO runs the higher net margin — AMGN at 22.93% versus NVO at 35.33%.
How have AMGN and NVO total returns compared?
Over the past 10 years, AMGN delivered 11.80% and NVO delivered 9.46% annualized total return. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified September 13, 2026.