Which has the lower trailing P/E, AMGN or MRK?

AMGN has the lower trailing P/E: AMGN trades at 26.18 and MRK at 36.83. P/E is one valuation measure and does not by itself establish which business is cheaper.

Which has grown faster, AMGN or MRK?

Over the past five years, MRK grew revenue faster — AMGN at a 8.15% CAGR versus MRK at 8.60%.

Does AMGN or MRK pay a bigger dividend?

AMGN yields 2.60% and MRK yields 2.57% based on trailing dividends and the latest price.

Is AMGN or MRK more profitable?

AMGN runs the higher net margin — AMGN at 20.95% versus MRK at 13.62%.

How have AMGN and MRK total returns compared?

Over the past 10 years, AMGN delivered 11.95% and MRK delivered 12.27% annualized total return. Past performance doesn't predict future results.

Amgen Inc. (AMGN) vs Merck & Co., Inc. (MRK)

A side-by-side comparison of Amgen Inc. and Merck & Co., Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of July 28, 2026. Differences are shown without an overall score or investment verdict.

AMGN

Amgen Inc.

$212.16B

$393.10HealthcareDelayed quote: Jul 28, 2026, 4:00 PM EDT

MRK

Merck & Co., Inc.

$325.61B

$131.84HealthcareDelayed quote: Jul 28, 2026, 3:59 PM EDT

Total return — AMGN vs MRK

growth of $100 · dividends reinvested · last 30y

AMGN +3992.1%MRK +990.2%AMGN compounded faster

AMGN MRK

AMGN vs MRK: by the numbers

•MRK is the larger company ($325.61B vs $212.16B market cap).
•AMGN trades at the lower trailing earnings multiple (26.18 vs 36.83 P/E), one valuation lens rather than an overall verdict.
•AMGN converts more revenue to profit (20.95% vs 13.62% net margin).
•MRK grew revenue faster over the past five years (8.60% vs 8.15% CAGR).
•AMGN pays the higher dividend yield (2.60% vs 2.57%).

Metrics side by side

Valuation

Metric	AMGN	MRK
P/E ratio	26.18	36.83
Forward P/E	16.84	47.09
P/S ratio	5.50	4.93
P/B ratio	22.27	7.05
PEG ratio	0.26	1.81
EV / EBITDA	14.99	15.16
FCF yield	4.20%	4.37%

Profitability

Metric	AMGN	MRK
Gross margin	71.46%	75.91%
Operating margin	31.63%	36.17%
Net margin	20.95%	13.62%
ROE	84.87%	19.48%
ROIC	13.16%	18.27%

Dividends

Metric	AMGN	MRK
Dividend yield	2.60%	2.57%
Payout ratio	68.39%	46.03%

Growth (annualized)

Metric	AMGN	MRK
Revenue CAGR (5Y)	8.15%	8.60%
EPS CAGR (5Y)	2.94%	21.21%
FCF CAGR (5Y)	-2.66%	15.69%
Total return CAGR (5Y)	13.52%	14.44%

Frequently asked

Which has the lower trailing P/E, AMGN or MRK?: AMGN has the lower trailing P/E: AMGN trades at 26.18 and MRK at 36.83. P/E is one valuation measure and does not by itself establish which business is cheaper.
Which has grown faster, AMGN or MRK?: Over the past five years, MRK grew revenue faster — AMGN at a 8.15% CAGR versus MRK at 8.60%.
Does AMGN or MRK pay a bigger dividend?: AMGN yields 2.60% and MRK yields 2.57% based on trailing dividends and the latest price.
Is AMGN or MRK more profitable?: AMGN runs the higher net margin — AMGN at 20.95% versus MRK at 13.62%.
How have AMGN and MRK total returns compared?: Over the past 10 years, AMGN delivered 11.95% and MRK delivered 12.27% annualized total return. Past performance doesn't predict future results.

Go deeper

Full AMGN analysis Full MRK analysis Interactive comparison tool

Dig into the metrics

Amgen P/E ratio Merck & P/E ratio Amgen dividend yield Merck & dividend yield Amgen ROE Merck & ROE Amgen operating margin Merck & operating margin Amgen revenue growth Merck & revenue growth Amgen free cash flow Merck & free cash flow

Amgen & Merck & appear in these rankings

Highest Dividend Yield Stocks Highest ROE Stocks Highest ROIC Stocks Highest Operating Margin Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified July 28, 2026.