Which has the lower trailing P/E, AMGN or MRK?

AMGN has the lower trailing P/E: AMGN trades at 23.38 and MRK at 114.68. P/E is one valuation measure and does not by itself establish which business is cheaper.

Which has grown faster, AMGN or MRK?

Over the past five years, AMGN grew revenue faster — AMGN at a 8.39% CAGR versus MRK at 7.87%.

Does AMGN or MRK pay a bigger dividend?

AMGN yields 2.63% and MRK yields 2.33% based on trailing dividends and the latest price.

Is AMGN or MRK more profitable?

AMGN runs the higher net margin — AMGN at 22.93% versus MRK at 4.78%.

How have AMGN and MRK total returns compared?

Over the past 10 years, AMGN delivered 11.80% and MRK delivered 12.62% annualized total return. Past performance doesn't predict future results.

Amgen Inc. (AMGN) vs Merck & Co., Inc. (MRK)

A side-by-side comparison of Amgen Inc. and Merck & Co., Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of September 13, 2026. Differences are shown without an overall score or investment verdict.

AMGN

Amgen Inc.

$202.99B

$376.12HealthcareDelayed quote: Sep 15, 2026, 10:30 AM EDT

MRK

Merck & Co., Inc.

$354.05B

$143.35HealthcareDelayed quote: Sep 15, 2026, 10:30 AM EDT

Total return — AMGN vs MRK

growth of $100 · dividends reinvested · last 10y

AMGN +197.8% (+11.5%/yr)MRK +226.9% (+12.6%/yr)MRK compounded faster over this window

AMGN MRK

AMGN vs MRK: by the numbers

•MRK is the larger company ($354.05B vs $202.99B market cap).
•AMGN trades at the lower trailing earnings multiple (23.38 vs 114.68 P/E), one valuation lens rather than an overall verdict.
•AMGN converts more revenue to profit (22.93% vs 4.78% net margin).
•AMGN grew revenue faster over the past five years (8.39% vs 7.87% CAGR).
•AMGN pays the higher dividend yield (2.63% vs 2.33%).

Metrics side by side

Valuation

Metric	AMGN	MRK
P/E ratio	23.38	114.68
Forward P/E	16.30	52.20
P/S ratio	5.32	5.33
P/B ratio	17.37	8.44
EV / EBITDA	N/A	22.68
FCF yield	5.01%	4.54%

Profitability

Metric	AMGN	MRK
Gross margin	72.65%	75.38%
Operating margin	33.18%	36.17%
Net margin	22.93%	4.78%
ROE	74.80%	7.57%
ROIC	14.22%	5.80%

Dividends

Metric	AMGN	MRK
Dividend yield	2.63%	2.33%
Payout ratio	61.78%	268.80%

Growth (annualized)

Metric	AMGN	MRK
Revenue CAGR (5Y)	8.39%	7.87%
EPS CAGR (5Y)	2.94%	21.21%
FCF CAGR (5Y)	-3.91%	23.61%
Total return CAGR (5Y)	15.58%	18.01%

Frequently asked

Which has the lower trailing P/E, AMGN or MRK?: AMGN has the lower trailing P/E: AMGN trades at 23.38 and MRK at 114.68. P/E is one valuation measure and does not by itself establish which business is cheaper.
Which has grown faster, AMGN or MRK?: Over the past five years, AMGN grew revenue faster — AMGN at a 8.39% CAGR versus MRK at 7.87%.
Does AMGN or MRK pay a bigger dividend?: AMGN yields 2.63% and MRK yields 2.33% based on trailing dividends and the latest price.
Is AMGN or MRK more profitable?: AMGN runs the higher net margin — AMGN at 22.93% versus MRK at 4.78%.
How have AMGN and MRK total returns compared?: Over the past 10 years, AMGN delivered 11.80% and MRK delivered 12.62% annualized total return. Past performance doesn't predict future results.

Go deeper

Full AMGN analysis Full MRK analysis Interactive comparison tool

Dig into the metrics

Amgen P/E ratio Merck P/E ratio Amgen dividend yield Merck dividend yield Amgen ROE Merck ROE Amgen operating margin Merck operating margin Amgen revenue growth Merck revenue growth Amgen free cash flow Merck free cash flow

Amgen & Merck appear in these rankings

Highest Dividend Yield Stocks Highest ROE Stocks Highest Operating Margin Stocks Highest FCF Yield Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified September 13, 2026.