Amgen Inc. (AMGN) vs Eli Lilly and Company (LLY)

A side-by-side comparison of Amgen Inc. and Eli Lilly and Company across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of September 10, 2026. Differences are shown without an overall score or investment verdict.

Compare

Total returnAMGN vs LLY

growth of $100 · dividends reinvested · last 10y
AMGN +201.9% (+11.7%/yr)LLY +1566.6% (+32.5%/yr)LLY compounded faster over this window
Log scale — wide-divergence pair
101001k10kStart $10020182020202220242026$302$1,667
AMGN LLY

AMGN vs LLY: by the numbers

  • LLY is the larger company ($1.05T vs $203.66B market cap).
  • AMGN trades at the lower trailing earnings multiple (23.45 vs 37.42 P/E), one valuation lens rather than an overall verdict.
  • LLY converts more revenue to profit (33.53% vs 22.93% net margin).
  • LLY grew revenue faster over the past five years (24.42% vs 8.39% CAGR).
  • AMGN pays the higher dividend yield (2.56% vs 0.60%).

Metrics side by side

Valuation

MetricAMGNLLY
P/E ratio23.4537.42
Forward P/E16.3530.64
P/S ratio5.3413.18
P/B ratio17.4231.00
EV / EBITDAN/A29.91
FCF yield5.00%1.91%

Profitability

MetricAMGNLLY
Gross margin72.65%84.01%
Operating margin33.18%43.92%
Net margin22.93%33.53%
ROE74.80%78.84%
ROIC14.22%27.38%

Dividends

MetricAMGNLLY
Dividend yield2.56%0.60%
Payout ratio60.91%22.45%

Growth (annualized)

MetricAMGNLLY
Revenue CAGR (5Y)8.39%24.42%
EPS CAGR (5Y)2.94%28.88%
FCF CAGR (5Y)-3.91%32.91%
Total return CAGR (5Y)15.90%37.46%

Frequently asked

Which has the lower trailing P/E, AMGN or LLY?
AMGN has the lower trailing P/E: AMGN trades at 23.45 and LLY at 37.42. P/E is one valuation measure and does not by itself establish which business is cheaper.
Which has grown faster, AMGN or LLY?
Over the past five years, LLY grew revenue faster — AMGN at a 8.39% CAGR versus LLY at 24.42%.
Does AMGN or LLY pay a bigger dividend?
AMGN yields 2.56% and LLY yields 0.60% based on trailing dividends and the latest price.
Is AMGN or LLY more profitable?
LLY runs the higher net margin — AMGN at 22.93% versus LLY at 33.53%.
How have AMGN and LLY total returns compared?
Over the past 10 years, AMGN delivered 11.95% and LLY delivered 32.58% annualized total return. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified September 10, 2026.