Amgen Inc. (AMGN) vs Gilead Sciences, Inc. (GILD)
A side-by-side comparison of Amgen Inc. and Gilead Sciences, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of September 10, 2026. Differences are shown without an overall score or investment verdict.
AMGN
Amgen Inc.
$377.35HealthcareDelayed quote: Sep 11, 2026, 4:00 PM EDT
GILD
Gilead Sciences, Inc.
$143.72HealthcareDelayed quote: Sep 11, 2026, 4:00 PM EDT
Total return — AMGN vs GILD
growth of $100 · dividends reinvested · last 10yAMGN +200.6% (+11.6%/yr)GILD +161.3% (+10.1%/yr)AMGN compounded faster over this window
AMGN GILD
AMGN vs GILD: by the numbers
- •AMGN is the larger company ($203.66B vs $178.44B market cap).
- •AMGN is profitable (22.93% net margin) while GILD runs a net loss (-10.64%).
- •AMGN grew revenue faster over the past five years (8.39% vs 2.72% CAGR).
- •AMGN pays the higher dividend yield (2.56% vs 2.22%).
Metrics side by side
Valuation
| Metric | AMGN | GILD |
|---|---|---|
| P/E ratio | 23.45 | N/A |
| Forward P/E | 16.35 | N/A |
| P/S ratio | 5.34 | 5.86 |
| P/B ratio | 17.42 | 15.09 |
| FCF yield | 5.00% | 7.27% |
Profitability
| Metric | AMGN | GILD |
|---|---|---|
| Gross margin | 72.65% | 79.59% |
| Operating margin | 33.18% | 39.74% |
| Net margin | 22.93% | -10.64% |
| ROE | 74.80% | -27.39% |
| ROIC | 14.22% | -3.66% |
Dividends
| Metric | AMGN | GILD |
|---|---|---|
| Dividend yield | 2.56% | 2.22% |
| Payout ratio | 60.91% | N/A |
Growth (annualized)
| Metric | AMGN | GILD |
|---|---|---|
| Revenue CAGR (5Y) | 8.39% | 2.72% |
| EPS CAGR (5Y) | 2.94% | 133.83% |
| FCF CAGR (5Y) | -3.91% | 9.27% |
| Total return CAGR (5Y) | 15.90% | 19.60% |
Frequently asked
- Which has grown faster, AMGN or GILD?
- Over the past five years, AMGN grew revenue faster — AMGN at a 8.39% CAGR versus GILD at 2.72%.
- Does AMGN or GILD pay a bigger dividend?
- AMGN yields 2.56% and GILD yields 2.22% based on trailing dividends and the latest price.
- Is AMGN or GILD more profitable?
- AMGN runs the higher net margin — AMGN at 22.93% versus GILD at -10.64%.
- How have AMGN and GILD total returns compared?
- Over the past 10 years, AMGN delivered 11.95% and GILD delivered 10.21% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Amgen P/E ratioAmgen dividend yieldGilead Sciences dividend yieldAmgen ROEGilead Sciences ROEAmgen operating marginGilead Sciences operating marginAmgen revenue growthGilead Sciences revenue growthAmgen free cash flowGilead Sciences free cash flow
Amgen & Gilead Sciences appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified September 10, 2026.