Amgen Inc. (AMGN) vs Gilead Sciences, Inc. (GILD)

A side-by-side comparison of Amgen Inc. and Gilead Sciences, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of September 10, 2026. Differences are shown without an overall score or investment verdict.

Compare

Total returnAMGN vs GILD

growth of $100 · dividends reinvested · last 10y
AMGN +200.6% (+11.6%/yr)GILD +161.3% (+10.1%/yr)AMGN compounded faster over this window
100200300Start $10020182020202220242026$301$261
AMGN GILD

AMGN vs GILD: by the numbers

  • AMGN is the larger company ($203.66B vs $178.44B market cap).
  • AMGN is profitable (22.93% net margin) while GILD runs a net loss (-10.64%).
  • AMGN grew revenue faster over the past five years (8.39% vs 2.72% CAGR).
  • AMGN pays the higher dividend yield (2.56% vs 2.22%).

Metrics side by side

Valuation

MetricAMGNGILD
P/E ratio23.45N/A
Forward P/E16.35N/A
P/S ratio5.345.86
P/B ratio17.4215.09
FCF yield5.00%7.27%

Profitability

MetricAMGNGILD
Gross margin72.65%79.59%
Operating margin33.18%39.74%
Net margin22.93%-10.64%
ROE74.80%-27.39%
ROIC14.22%-3.66%

Dividends

MetricAMGNGILD
Dividend yield2.56%2.22%
Payout ratio60.91%N/A

Growth (annualized)

MetricAMGNGILD
Revenue CAGR (5Y)8.39%2.72%
EPS CAGR (5Y)2.94%133.83%
FCF CAGR (5Y)-3.91%9.27%
Total return CAGR (5Y)15.90%19.60%

Frequently asked

Which has grown faster, AMGN or GILD?
Over the past five years, AMGN grew revenue faster — AMGN at a 8.39% CAGR versus GILD at 2.72%.
Does AMGN or GILD pay a bigger dividend?
AMGN yields 2.56% and GILD yields 2.22% based on trailing dividends and the latest price.
Is AMGN or GILD more profitable?
AMGN runs the higher net margin — AMGN at 22.93% versus GILD at -10.64%.
How have AMGN and GILD total returns compared?
Over the past 10 years, AMGN delivered 11.95% and GILD delivered 10.21% annualized total return. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified September 10, 2026.