Which has the lower trailing P/E, AMGN or AZN?

AMGN has the lower trailing P/E: AMGN trades at 23.45 and AZN at 24.05. P/E is one valuation measure and does not by itself establish which business is cheaper.

Which has grown faster, AMGN or AZN?

Over the past five years, AZN grew revenue faster — AMGN at a 8.39% CAGR versus AZN at 15.76%.

Does AMGN or AZN pay a bigger dividend?

AMGN yields 2.56% and AZN yields 2.02% based on trailing dividends and the latest price.

Is AMGN or AZN more profitable?

AMGN runs the higher net margin — AMGN at 22.93% versus AZN at 17.02%.

How have AMGN and AZN total returns compared?

Over the past 10 years, AMGN delivered 11.95% and AZN delivered 12.85% annualized total return. Past performance doesn't predict future results.

Amgen Inc. (AMGN) vs AstraZeneca PLC (AZN)

A side-by-side comparison of Amgen Inc. and AstraZeneca PLC across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of September 10, 2026. Differences are shown without an overall score or investment verdict.

AMGN

Amgen Inc.

$203.66B

$377.35HealthcareDelayed quote: Sep 11, 2026, 4:00 PM EDT

AZN

AstraZeneca PLC

$248.40B

$160.17HealthcareDelayed quote: Sep 11, 2026, 4:00 PM EDT

Total return — AMGN vs AZN

growth of $100 · dividends reinvested · last 10y

AMGN +200.6% (+11.6%/yr)AZN +217.1% (+12.2%/yr)AZN compounded faster over this window

AMGN AZN

AMGN vs AZN: by the numbers

•AZN is the larger company ($248.40B vs $203.66B market cap).
•AMGN trades at the lower trailing earnings multiple (23.45 vs 24.05 P/E), one valuation lens rather than an overall verdict.
•AMGN converts more revenue to profit (22.93% vs 17.02% net margin).
•AZN grew revenue faster over the past five years (15.76% vs 8.39% CAGR).
•AMGN pays the higher dividend yield (2.56% vs 2.02%).

Metrics side by side

Valuation

Metric	AMGN	AZN
P/E ratio	23.45	24.05
Forward P/E	16.35	15.64
P/S ratio	5.34	4.05
P/B ratio	17.42	4.94
EV / EBITDA	N/A	13.56
FCF yield	5.00%	3.52%

Profitability

Metric	AMGN	AZN
Gross margin	72.65%	81.88%
Operating margin	33.18%	22.77%
Net margin	22.93%	17.02%
ROE	74.80%	20.79%
ROIC	14.22%	12.83%

Dividends

Metric	AMGN	AZN
Dividend yield	2.56%	2.02%
Payout ratio	60.91%	48.50%

Growth (annualized)

Metric	AMGN	AZN
Revenue CAGR (5Y)	8.39%	15.76%
EPS CAGR (5Y)	2.94%	22.02%
FCF CAGR (5Y)	-3.91%	14.53%
Total return CAGR (5Y)	15.90%	9.46%

Frequently asked

Which has the lower trailing P/E, AMGN or AZN?: AMGN has the lower trailing P/E: AMGN trades at 23.45 and AZN at 24.05. P/E is one valuation measure and does not by itself establish which business is cheaper.
Which has grown faster, AMGN or AZN?: Over the past five years, AZN grew revenue faster — AMGN at a 8.39% CAGR versus AZN at 15.76%.
Does AMGN or AZN pay a bigger dividend?: AMGN yields 2.56% and AZN yields 2.02% based on trailing dividends and the latest price.
Is AMGN or AZN more profitable?: AMGN runs the higher net margin — AMGN at 22.93% versus AZN at 17.02%.
How have AMGN and AZN total returns compared?: Over the past 10 years, AMGN delivered 11.95% and AZN delivered 12.85% annualized total return. Past performance doesn't predict future results.

Go deeper

Full AMGN analysis Full AZN analysis Interactive comparison tool

Dig into the metrics

Amgen P/E ratio AstraZeneca P/E ratio Amgen dividend yield AstraZeneca dividend yield Amgen ROE AstraZeneca ROE Amgen operating margin AstraZeneca operating margin Amgen revenue growth AstraZeneca revenue growth Amgen free cash flow AstraZeneca free cash flow

Amgen & AstraZeneca appear in these rankings

Highest Dividend Yield Stocks Fastest Revenue Growth Stocks Highest ROE Stocks Highest Operating Margin Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified September 10, 2026.