Amgen Inc. (AMGN) vs AstraZeneca PLC (AZN)
AZN leads on 8 of 15 compared metrics, though AMGN is the cheaper stock.
A side-by-side comparison of Amgen Inc. and AstraZeneca PLC across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of June 13, 2026. The ● marks the stronger figure on each row (cheaper multiple, higher margin/return).
Total return — AMGN vs AZN
growth of $100 · last 30yAMGN +2282.3%AZN +723.4%AMGN compounded faster
AMGN AZN
AMGN vs AZN: by the numbers
- •AZN is the larger company ($277.22B vs $191.70B market cap).
- •AMGN trades at the lower earnings multiple (24.72 vs 26.92 P/E).
- •AMGN converts more revenue to profit (20.95% vs 17.19% net margin).
- •AZN grew revenue faster over the past five years (16.99% vs 8.15% CAGR).
- •AMGN pays the higher dividend yield (2.76% vs 1.79%).
Which is better, AMGN or AZN?
Metric tally: AMGN 7 · AZN 8It depends on what you're optimizing for:
ValueAMGN(lower P/E)
GrowthAZN(faster 5Y revenue CAGR)
IncomeAMGN(higher dividend yield)
Valuation
| Metric | AMGN | AZN |
|---|---|---|
| P/E ratio | 24.72● | 26.92 |
| Forward P/E | 15.15 | 15.33 |
| P/S ratio | 5.19 | 4.62● |
| P/B ratio | 21.03 | 5.90● |
| PEG ratio | 0.26 | 0.14● |
| EV / EBITDA | 15.32 | 14.92● |
| FCF yield | 4.45%● | 3.26% |
Profitability
| Metric | AMGN | AZN |
|---|---|---|
| Gross margin | 71.46% | 81.68%● |
| Operating margin | 31.63%● | 23.69% |
| Net margin | 20.95%● | 17.19% |
| ROE | 84.87%● | 21.95% |
| ROIC | 13.16% | 13.03% |
Dividends
| Metric | AMGN | AZN |
|---|---|---|
| Dividend yield | 2.76%● | 1.79% |
| Payout ratio | 68.39% | 48.48% |
Growth (annualized)
| Metric | AMGN | AZN |
|---|---|---|
| Revenue CAGR (5Y) | 8.15% | 16.99%● |
| EPS CAGR (5Y) | 2.94% | 22.02%● |
| FCF CAGR (5Y) | -2.66% | 18.52%● |
| Total return CAGR (5Y) | 11.36%● | 11.03% |
Frequently asked
- Which is better, AMGN or AZN?
- It depends on your goal. value: AMGN (lower P/E); growth: AZN (faster 5Y revenue CAGR); income: AMGN (higher dividend yield). Across all compared metrics, AZN leads 8 to 7.
- Is AMGN or AZN cheaper?
- On trailing earnings, AMGN is cheaper: AMGN trades at a 24.72 P/E and AZN at 26.92.
- Which has grown faster, AMGN or AZN?
- Over the past five years, AZN grew revenue faster — AMGN at a 8.15% CAGR versus AZN at 16.99%.
- Does AMGN or AZN pay a bigger dividend?
- AMGN yields 2.76% and AZN yields 1.79% based on trailing dividends and the latest price.
- Is AMGN or AZN more profitable?
- AMGN runs the higher net margin — AMGN at 20.95% versus AZN at 17.19%.
- Which has been the better investment, AMGN or AZN?
- Over the past 10-year, AZN delivered the higher annualized total return — AMGN at 11.94% versus AZN at 15.77%. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Amgen P/E ratioAstraZeneca P/E ratioAmgen dividend yieldAstraZeneca dividend yieldAmgen ROEAstraZeneca ROEAmgen operating marginAstraZeneca operating marginAmgen revenue growthAstraZeneca revenue growthAmgen free cash flowAstraZeneca free cash flow
Amgen & AstraZeneca appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified June 13, 2026.