Advanced Micro Devices, Inc. (AMD) vs Pfizer Inc. (PFE)

A side-by-side comparison of Advanced Micro Devices, Inc. and Pfizer Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of September 10, 2026. Differences are shown without an overall score or investment verdict.

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Different business models: AMD is classified in Technology; PFE is classified in Healthcare. Margin, capital intensity, and valuation differences should be interpreted in that sector context.

Total returnAMD vs PFE

growth of $100 · dividends reinvested · last 10y
AMD +6882.0% (+52.9%/yr)PFE +37.3% (+3.2%/yr)AMD compounded faster over this window
Log scale — wide-divergence pair
101001k10kStart $10020182020202220242026$6,982$137
AMD PFE

AMD vs PFE: by the numbers

  • AMD is the larger company ($841.60B vs $157.99B market cap).
  • PFE trades at the lower trailing earnings multiple (36.63 vs 132.34 P/E), one valuation lens rather than an overall verdict.
  • AMD converts more revenue to profit (15.58% vs 6.81% net margin).
  • AMD grew revenue faster over the past five years (25.35% vs 6.29% CAGR).
  • PFE pays a dividend (6.19% yield), while AMD is a former payer with no current dividend run rate.

Metrics side by side

Valuation

MetricAMDPFE
P/E ratio132.3436.63
Forward P/E68.369.32
P/S ratio20.382.48
P/B ratio12.521.85
EV / EBITDA88.3610.15
FCF yield1.00%6.95%

Profitability

MetricAMDPFE
Gross margin53.20%71.32%
Operating margin15.71%25.08%
Net margin15.58%6.81%
ROE9.57%5.09%
ROIC7.58%9.33%

Dividends

MetricAMDPFE
Dividend yieldN/A6.19%
Payout ratioN/A227.27%

Growth (annualized)

MetricAMDPFE
Revenue CAGR (5Y)25.35%6.29%
EPS CAGR (5Y)4.92%-3.78%
FCF CAGR (5Y)27.78%-3.11%
Total return CAGR (5Y)36.78%-4.68%

Frequently asked

Which has the lower trailing P/E, AMD or PFE?
PFE has the lower trailing P/E: AMD trades at 132.34 and PFE at 36.63. P/E is one valuation measure and does not by itself establish which business is cheaper.
Which has grown faster, AMD or PFE?
Over the past five years, AMD grew revenue faster — AMD at a 25.35% CAGR versus PFE at 6.29%.
Does AMD or PFE pay a bigger dividend?
PFE pays a dividend (6.19% yield), while AMD is a former payer with no current dividend run rate.
Is AMD or PFE more profitable?
AMD runs the higher net margin — AMD at 15.58% versus PFE at 6.81%.
How have AMD and PFE total returns compared?
Over the past 10 years, AMD delivered 55.99% and PFE delivered 3.17% annualized total return. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified September 10, 2026.