Advanced Micro Devices, Inc. (AMD) vs Merck & Co., Inc. (MRK)

A side-by-side comparison of Advanced Micro Devices, Inc. and Merck & Co., Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of September 10, 2026. Differences are shown without an overall score or investment verdict.

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Different business models: AMD is classified in Technology; MRK is classified in Healthcare. Margin, capital intensity, and valuation differences should be interpreted in that sector context.

Total returnAMD vs MRK

growth of $100 · dividends reinvested · last 10y
AMD +7262.6% (+53.7%/yr)MRK +228.7% (+12.6%/yr)AMD compounded faster over this window
Log scale — wide-divergence pair
101001k10kStart $10020182020202220242026$7,363$329
AMD MRK

AMD vs MRK: by the numbers

  • AMD is the larger company ($841.60B vs $355.49B market cap).
  • MRK trades at the lower trailing earnings multiple (115.15 vs 132.34 P/E), one valuation lens rather than an overall verdict.
  • AMD converts more revenue to profit (15.58% vs 4.78% net margin).
  • AMD grew revenue faster over the past five years (25.35% vs 7.87% CAGR).
  • MRK pays a dividend (2.32% yield), while AMD is a former payer with no current dividend run rate.

Metrics side by side

Valuation

MetricAMDMRK
P/E ratio132.34115.15
Forward P/E68.3652.41
P/S ratio20.385.35
P/B ratio12.528.48
EV / EBITDA88.3622.76
FCF yield1.00%4.52%

Profitability

MetricAMDMRK
Gross margin53.20%75.38%
Operating margin15.71%36.17%
Net margin15.58%4.78%
ROE9.57%7.57%
ROIC7.58%5.80%

Dividends

MetricAMDMRK
Dividend yieldN/A2.32%
Payout ratioN/A268.80%

Growth (annualized)

MetricAMDMRK
Revenue CAGR (5Y)25.35%7.87%
EPS CAGR (5Y)4.92%21.21%
FCF CAGR (5Y)27.78%23.61%
Total return CAGR (5Y)36.78%18.15%

Frequently asked

Which has the lower trailing P/E, AMD or MRK?
MRK has the lower trailing P/E: AMD trades at 132.34 and MRK at 115.15. P/E is one valuation measure and does not by itself establish which business is cheaper.
Which has grown faster, AMD or MRK?
Over the past five years, AMD grew revenue faster — AMD at a 25.35% CAGR versus MRK at 7.87%.
Does AMD or MRK pay a bigger dividend?
MRK pays a dividend (2.32% yield), while AMD is a former payer with no current dividend run rate.
Is AMD or MRK more profitable?
AMD runs the higher net margin — AMD at 15.58% versus MRK at 4.78%.
How have AMD and MRK total returns compared?
Over the past 10 years, AMD delivered 55.99% and MRK delivered 12.68% annualized total return. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified September 10, 2026.