Alnylam Pharmaceuticals, Inc. (ALNY) vs Zoetis Inc. (ZTS)

A side-by-side comparison of Alnylam Pharmaceuticals, Inc. and Zoetis Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of August 29, 2026. Differences are shown without an overall score or investment verdict.

Compare

Total returnALNY vs ZTS

growth of $100 · dividends reinvested · last 10y
ALNY +231.3% (+12.7%/yr)ZTS +66.3% (+5.2%/yr)ALNY compounded faster over this window
0200400600Start $10020182020202220242026$331$166
ALNY ZTS

ALNY vs ZTS: by the numbers

  • ZTS is the larger company ($32.42B vs $31.73B market cap).
  • ZTS trades at the lower trailing earnings multiple (12.74 vs 40.05 P/E), one valuation lens rather than an overall verdict.
  • ZTS converts more revenue to profit (27.49% vs 16.82% net margin).
  • ALNY grew revenue faster over the past five years (47.53% vs 5.13% CAGR).
  • ZTS pays a dividend (2.66% yield), while ALNY has no payments in the available dividend history.

Metrics side by side

Valuation

MetricALNYZTS
P/E ratio40.0512.74
Forward P/E36.4312.37
P/S ratio6.823.39
P/B ratio24.2110.26
EV / EBITDA30.6810.01
FCF yield1.66%7.33%

Profitability

MetricALNYZTS
Gross margin79.72%70.87%
Operating margin20.81%37.00%
Net margin16.82%27.49%
ROE59.67%83.10%
ROIC24.71%21.63%

Dividends

MetricALNYZTS
Dividend yieldN/A2.66%
Payout ratioN/A34.16%

Growth (annualized)

MetricALNYZTS
Revenue CAGR (5Y)47.53%5.13%
EPS CAGR (5Y)N/A11.88%
FCF CAGR (5Y)N/A6.81%
Total return CAGR (5Y)3.06%-16.68%

Frequently asked

Which has the lower trailing P/E, ALNY or ZTS?
ZTS has the lower trailing P/E: ALNY trades at 40.05 and ZTS at 12.74. P/E is one valuation measure and does not by itself establish which business is cheaper.
Which has grown faster, ALNY or ZTS?
Over the past five years, ALNY grew revenue faster — ALNY at a 47.53% CAGR versus ZTS at 5.13%.
Does ALNY or ZTS pay a bigger dividend?
ZTS pays a dividend (2.66% yield), while ALNY has no payments in the available dividend history.
Is ALNY or ZTS more profitable?
ZTS runs the higher net margin — ALNY at 16.82% versus ZTS at 27.49%.
How have ALNY and ZTS total returns compared?
Over the past 10 years, ALNY delivered 12.84% and ZTS delivered 5.22% annualized total return. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified August 29, 2026.