Alnylam Pharmaceuticals, Inc. (ALNY) vs Mettler-Toledo International Inc. (MTD)

A side-by-side comparison of Alnylam Pharmaceuticals, Inc. and Mettler-Toledo International Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 2, 2026. Differences are shown without an overall score or investment verdict.

Compare

Total return — ALNY vs MTD

growth of $100 · dividends reinvested · last 10y
ALNY +238.8% (+13.0%/yr)MTD +262.9% (+13.8%/yr)MTD compounded faster over this window
0200400600Start $10020182020202220242026$339$363
ALNY MTD

ALNY vs MTD: by the numbers

  • •ALNY is the larger company ($30.93B vs $29.93B market cap).
  • •MTD trades at the lower trailing earnings multiple (33.34 vs 39.05 P/E), one valuation lens rather than an overall verdict.
  • •MTD converts more revenue to profit (21.91% vs 16.82% net margin).
  • •ALNY grew revenue faster over the past five years (47.53% vs 3.54% CAGR).

Metrics side by side

Valuation

MetricALNYMTD
P/E ratio39.0533.34
Forward P/E34.6731.30
P/S ratio6.447.24
P/B ratio22.842334.16
EV / EBITDA28.9324.51
FCF yield1.75%2.89%

Profitability

MetricALNYMTD
Gross margin79.72%58.35%
Operating margin20.81%28.41%
Net margin16.82%21.91%
ROE59.67%7062.40%
ROIC24.71%38.19%

Growth (annualized)

MetricALNYMTD
Revenue CAGR (5Y)47.53%3.54%
EPS CAGR (5Y)N/A10.81%
FCF CAGR (5Y)N/A2.13%
Total return CAGR (5Y)3.71%1.28%

Frequently asked

Which has the lower trailing P/E, ALNY or MTD?
MTD has the lower trailing P/E: ALNY trades at 39.05 and MTD at 33.34. P/E is one valuation measure and does not by itself establish which business is cheaper.
Which has grown faster, ALNY or MTD?
Over the past five years, ALNY grew revenue faster — ALNY at a 47.53% CAGR versus MTD at 3.54%.
Is ALNY or MTD more profitable?
MTD runs the higher net margin — ALNY at 16.82% versus MTD at 21.91%.
How have ALNY and MTD total returns compared?
Over the past 10 years, ALNY delivered 13.05% and MTD delivered 13.43% annualized total return. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 2, 2026.