Alnylam Pharmaceuticals, Inc. (ALNY) vs Humana Inc. (HUM)

ALNY leads on 9 of 14 compared metrics, though HUM is the cheaper stock.

A side-by-side comparison of Alnylam Pharmaceuticals, Inc. and Humana Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of July 20, 2026. The ● marks the stronger figure on each row (cheaper multiple, higher margin/return).

Compare

Total returnALNY vs HUM

growth of $100 · dividends reinvested · last 22y
ALNY +4444.9%HUM +2560.7%ALNY compounded faster
02k4k6k8kStart $10020082012201620202024$4,545$2,661
ALNY HUM

ALNY vs HUM: by the numbers

  • HUM is the larger company ($47.81B vs $36.40B market cap).
  • HUM trades at the lower earnings multiple (42.59 vs 63.53 P/E).
  • ALNY converts more revenue to profit (13.46% vs 0.82% net margin).
  • ALNY grew revenue faster over the past five years (49.67% vs 11.71% CAGR).
  • HUM pays a dividend (0.89% yield) while ALNY does not currently pay one.

Which is better, ALNY or HUM?

Metric tally: ALNY 9 · HUM 5

It depends on what you're optimizing for:

ValueHUM(lower P/E)
GrowthALNY(faster 5Y revenue CAGR)
QualityALNY(higher ROIC)

Metrics side by side

Valuation

MetricALNYHUM
P/E ratio63.5342.59
Forward P/E35.9144.48
P/S ratio8.620.35
P/B ratio34.382.59
EV / EBITDA45.2726.10
FCF yield1.73%2.65%

Profitability

MetricALNYHUM
Gross margin80.89%14.01%
Operating margin17.54%1.01%
Net margin13.46%0.82%
ROE53.68%6.08%
ROIC13.74%3.12%

Dividends

MetricALNYHUM
Dividend yield0.89%
Payout ratio35.87%

Growth (annualized)

MetricALNYHUM
Revenue CAGR (5Y)49.67%11.71%
EPS CAGR (5Y)-17.27%
FCF CAGR (5Y)14.35%-17.19%
Total return CAGR (5Y)8.32%-1.89%

Frequently asked

Which is better, ALNY or HUM?
It depends on your goal. value: HUM (lower P/E); growth: ALNY (faster 5Y revenue CAGR); quality: ALNY (higher ROIC). Across all compared metrics, ALNY leads 9 to 5.
Is ALNY or HUM cheaper?
On trailing earnings, HUM is cheaper: ALNY trades at a 63.53 P/E and HUM at 42.59.
Which has grown faster, ALNY or HUM?
Over the past five years, ALNY grew revenue faster — ALNY at a 49.67% CAGR versus HUM at 11.71%.
Does ALNY or HUM pay a bigger dividend?
HUM pays a dividend (0.89% yield) while ALNY does not currently pay one.
Is ALNY or HUM more profitable?
ALNY runs the higher net margin — ALNY at 13.46% versus HUM at 0.82%.
Which has been the better investment, ALNY or HUM?
Over the past 10-year, ALNY delivered the higher annualized total return — ALNY at 15.31% versus HUM at 10.59%. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified July 20, 2026.