Alnylam Pharmaceuticals, Inc. (ALNY) vs Humana Inc. (HUM)
ALNY leads on 9 of 14 compared metrics, though HUM is the cheaper stock.
A side-by-side comparison of Alnylam Pharmaceuticals, Inc. and Humana Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of July 20, 2026. The ● marks the stronger figure on each row (cheaper multiple, higher margin/return).
ALNY
Alnylam Pharmaceuticals, Inc.
$272.67HealthcareDelayed quote: Jul 20, 2026, 4:00 PM EDT
HUM
Humana Inc.
$398.25HealthcareDelayed quote: Jul 20, 2026, 3:59 PM EDT
Total return — ALNY vs HUM
growth of $100 · dividends reinvested · last 22yALNY +4444.9%HUM +2560.7%ALNY compounded faster
ALNY HUM
ALNY vs HUM: by the numbers
- •HUM is the larger company ($47.81B vs $36.40B market cap).
- •HUM trades at the lower earnings multiple (42.59 vs 63.53 P/E).
- •ALNY converts more revenue to profit (13.46% vs 0.82% net margin).
- •ALNY grew revenue faster over the past five years (49.67% vs 11.71% CAGR).
- •HUM pays a dividend (0.89% yield) while ALNY does not currently pay one.
Which is better, ALNY or HUM?
Metric tally: ALNY 9 · HUM 5It depends on what you're optimizing for:
ValueHUM(lower P/E)
GrowthALNY(faster 5Y revenue CAGR)
QualityALNY(higher ROIC)
Metrics side by side
Valuation
| Metric | ALNY | HUM |
|---|---|---|
| P/E ratio | 63.53 | 42.59● |
| Forward P/E | 35.91● | 44.48 |
| P/S ratio | 8.62 | 0.35● |
| P/B ratio | 34.38 | 2.59● |
| EV / EBITDA | 45.27 | 26.10● |
| FCF yield | 1.73% | 2.65%● |
Profitability
| Metric | ALNY | HUM |
|---|---|---|
| Gross margin | 80.89%● | 14.01% |
| Operating margin | 17.54%● | 1.01% |
| Net margin | 13.46%● | 0.82% |
| ROE | 53.68%● | 6.08% |
| ROIC | 13.74%● | 3.12% |
Dividends
| Metric | ALNY | HUM |
|---|---|---|
| Dividend yield | — | 0.89% |
| Payout ratio | — | 35.87% |
Growth (annualized)
| Metric | ALNY | HUM |
|---|---|---|
| Revenue CAGR (5Y) | 49.67%● | 11.71% |
| EPS CAGR (5Y) | — | -17.27% |
| FCF CAGR (5Y) | 14.35%● | -17.19% |
| Total return CAGR (5Y) | 8.32%● | -1.89% |
Frequently asked
- Which is better, ALNY or HUM?
- It depends on your goal. value: HUM (lower P/E); growth: ALNY (faster 5Y revenue CAGR); quality: ALNY (higher ROIC). Across all compared metrics, ALNY leads 9 to 5.
- Is ALNY or HUM cheaper?
- On trailing earnings, HUM is cheaper: ALNY trades at a 63.53 P/E and HUM at 42.59.
- Which has grown faster, ALNY or HUM?
- Over the past five years, ALNY grew revenue faster — ALNY at a 49.67% CAGR versus HUM at 11.71%.
- Does ALNY or HUM pay a bigger dividend?
- HUM pays a dividend (0.89% yield) while ALNY does not currently pay one.
- Is ALNY or HUM more profitable?
- ALNY runs the higher net margin — ALNY at 13.46% versus HUM at 0.82%.
- Which has been the better investment, ALNY or HUM?
- Over the past 10-year, ALNY delivered the higher annualized total return — ALNY at 15.31% versus HUM at 10.59%. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Alnylam Pharmaceuticals P/E ratioHumana P/E ratioAlnylam Pharmaceuticals dividend yieldHumana dividend yieldAlnylam Pharmaceuticals ROEHumana ROEAlnylam Pharmaceuticals operating marginHumana operating marginAlnylam Pharmaceuticals revenue growthHumana revenue growthAlnylam Pharmaceuticals free cash flowHumana free cash flow
Alnylam Pharmaceuticals & Humana appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified July 20, 2026.