Alnylam Pharmaceuticals, Inc. (ALNY) vs BioNTech SE (BNTX)

A side-by-side comparison of Alnylam Pharmaceuticals, Inc. and BioNTech SE across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of August 23, 2026. Differences are shown without an overall score or investment verdict.

Compare

Total returnALNY vs BNTX

growth of $100 · dividends reinvested · last 7y
ALNY +206.7% (+17.4%/yr)BNTX +729.5% (+35.3%/yr)BNTX compounded faster over this window
01k2k3kStart $100202120232025$307$830
ALNY BNTX

ALNY vs BNTX: by the numbers

  • ALNY is the larger company ($31.61B vs $29.28B market cap).
  • ALNY is profitable (16.82% net margin) while BNTX runs a net loss (-62.98%).
  • ALNY grew revenue faster over the past five years (47.53% vs 40.61% CAGR).

Metrics side by side

Valuation

MetricALNYBNTX
P/E ratio39.90N/A
Forward P/E36.30N/A
P/S ratio6.809.53
P/B ratio24.121.46
EV / EBITDA30.56N/A
FCF yield1.66%2.10%

Profitability

MetricALNYBNTX
Gross margin79.72%70.98%
Operating margin20.81%-22.63%
Net margin16.82%-62.98%
ROE59.67%-9.62%
ROIC24.71%-10.37%

Growth (annualized)

MetricALNYBNTX
Revenue CAGR (5Y)47.53%40.61%
Total return CAGR (5Y)3.61%-19.46%

Frequently asked

Which has grown faster, ALNY or BNTX?
Over the past five years, ALNY grew revenue faster — ALNY at a 47.53% CAGR versus BNTX at 40.61%.
Is ALNY or BNTX more profitable?
ALNY runs the higher net margin — ALNY at 16.82% versus BNTX at -62.98%.
How have ALNY and BNTX total returns compared?
Over the past 5 years, ALNY delivered 12.49% and BNTX delivered -19.46% annualized total return. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified August 23, 2026.