Which has the lower trailing P/E, ALNY or BIIB?

BIIB has the lower trailing P/E: ALNY trades at 40.05 and BIIB at 38.67. P/E is one valuation measure and does not by itself establish which business is cheaper.

Which has grown faster, ALNY or BIIB?

Over the past five years, ALNY grew revenue faster — ALNY at a 47.53% CAGR versus BIIB at -3.19%.

Is ALNY or BIIB more profitable?

ALNY runs the higher net margin — ALNY at 16.82% versus BIIB at 8.39%.

How have ALNY and BIIB total returns compared?

Over the past 10 years, ALNY delivered 12.84% and BIIB delivered -3.38% annualized total return. Past performance doesn't predict future results.

Alnylam Pharmaceuticals, Inc. (ALNY) vs Biogen Inc. (BIIB)

A side-by-side comparison of Alnylam Pharmaceuticals, Inc. and Biogen Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of August 30, 2026. Differences are shown without an overall score or investment verdict.

ALNY

Alnylam Pharmaceuticals, Inc.

$31.73B

$237.10HealthcareAt close: Aug 28, 2026, 4:00 PM ET

BIIB

Biogen Inc.

$32.28B

$218.50HealthcareAt close: Aug 28, 2026, 4:00 PM ET

Total return — ALNY vs BIIB

growth of $100 · dividends reinvested · last 10y

ALNY +231.3% (+12.7%/yr)BIIB -28.8% (-3.3%/yr)ALNY compounded faster over this window

ALNY BIIB

ALNY vs BIIB: by the numbers

•BIIB is the larger company ($32.28B vs $31.73B market cap).
•BIIB trades at the lower trailing earnings multiple (38.67 vs 40.05 P/E), one valuation lens rather than an overall verdict.
•ALNY converts more revenue to profit (16.82% vs 8.39% net margin).
•ALNY grew revenue faster over the past five years (47.53% vs -3.19% CAGR).

Metrics side by side

Valuation

Metric	ALNY	BIIB
P/E ratio	40.05	38.67
Forward P/E	36.43	17.54
P/S ratio	6.82	3.27
P/B ratio	24.21	1.72
EV / EBITDA	30.68	22.45
FCF yield	1.66%	9.14%

Profitability

Metric	ALNY	BIIB
Gross margin	79.72%	67.71%
Operating margin	20.81%	12.79%
Net margin	16.82%	8.39%
ROE	59.67%	4.43%
ROIC	24.71%	4.28%

Growth (annualized)

Metric	ALNY	BIIB
Revenue CAGR (5Y)	47.53%	-3.19%
EPS CAGR (5Y)	N/A	-18.67%
FCF CAGR (5Y)	N/A	-11.63%
Total return CAGR (5Y)	3.06%	-8.63%

Frequently asked

Which has the lower trailing P/E, ALNY or BIIB?: BIIB has the lower trailing P/E: ALNY trades at 40.05 and BIIB at 38.67. P/E is one valuation measure and does not by itself establish which business is cheaper.
Which has grown faster, ALNY or BIIB?: Over the past five years, ALNY grew revenue faster — ALNY at a 47.53% CAGR versus BIIB at -3.19%.
Is ALNY or BIIB more profitable?: ALNY runs the higher net margin — ALNY at 16.82% versus BIIB at 8.39%.
How have ALNY and BIIB total returns compared?: Over the past 10 years, ALNY delivered 12.84% and BIIB delivered -3.38% annualized total return. Past performance doesn't predict future results.

Go deeper

Full ALNY analysis Full BIIB analysis Interactive comparison tool

Dig into the metrics

Alnylam Pharmaceuticals P/E ratio Biogen P/E ratio Alnylam Pharmaceuticals ROE Biogen ROE Alnylam Pharmaceuticals operating margin Biogen operating margin Alnylam Pharmaceuticals revenue growth Biogen revenue growth Alnylam Pharmaceuticals free cash flow Biogen free cash flow

Alnylam Pharmaceuticals & Biogen appear in these rankings

Fastest Revenue Growth Stocks Highest ROE Stocks Highest ROIC Stocks Highest FCF Yield Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified August 30, 2026.