Is ALNY or BIIB cheaper?

On trailing earnings, BIIB is cheaper: ALNY trades at a 66.30 P/E and BIIB at 21.12.

Which has grown faster, ALNY or BIIB?

Over the past five years, ALNY grew revenue faster — ALNY at a 49.67% CAGR versus BIIB at -4.80%.

Is ALNY or BIIB more profitable?

BIIB runs the higher net margin — ALNY at 13.46% versus BIIB at 13.92%.

Which has been the better investment, ALNY or BIIB?

Over the past 10-year, ALNY delivered the higher annualized total return — ALNY at 15.78% versus BIIB at -2.74%. Past performance doesn't predict future results.

Alnylam Pharmaceuticals, Inc. (ALNY) vs Biogen Inc. (BIIB)

ALNY and BIIB are evenly matched — 7 metrics each of 14.

A side-by-side comparison of Alnylam Pharmaceuticals, Inc. and Biogen Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of July 16, 2026. The ● marks the stronger figure on each row (cheaper multiple, higher margin/return).

ALNY

Alnylam Pharmaceuticals, Inc.

$37.78B

$282.98HealthcareDelayed quote: Jul 16, 2026, 2:05 PM EDT

BIIB

Biogen Inc.

$30.64B

$207.53HealthcareDelayed quote: Jul 16, 2026, 2:05 PM EDT

Total return — ALNY vs BIIB

growth of $100 · dividends reinvested · last 22y

ALNY +4544.6%BIIB +225.2%ALNY compounded faster

Log scale — wide-divergence pair

ALNY BIIB

ALNY vs BIIB: by the numbers

•ALNY is the larger company ($37.78B vs $30.64B market cap).
•BIIB trades at the lower earnings multiple (21.12 vs 66.30 P/E).
•BIIB converts more revenue to profit (13.92% vs 13.46% net margin).
•ALNY grew revenue faster over the past five years (49.67% vs -4.80% CAGR).

Which is better, ALNY or BIIB?

Metric tally: ALNY 7 · BIIB 7

It depends on what you're optimizing for:

ValueBIIB(lower P/E)

GrowthALNY(faster 5Y revenue CAGR)

QualityALNY(higher ROIC)

Metrics side by side

Valuation

Metric	ALNY	BIIB
P/E ratio	66.30	21.12●
Forward P/E	37.62	14.28●
P/S ratio	9.00	2.97●
P/B ratio	35.88	1.57●
EV / EBITDA	47.27	13.35●
FCF yield	1.66%	8.96%●

Profitability

Metric	ALNY	BIIB
Gross margin	80.89%●	69.77%
Operating margin	17.54%●	15.65%
Net margin	13.46%	13.92%●
ROE	53.68%●	7.36%
ROIC	13.74%●	6.62%

Growth (annualized)

Metric	ALNY	BIIB
Revenue CAGR (5Y)	49.67%●	-4.80%
EPS CAGR (5Y)	—	-18.67%
FCF CAGR (5Y)	14.35%●	-3.59%
Total return CAGR (5Y)	10.18%●	-9.68%

Frequently asked

Which is better, ALNY or BIIB?: It depends on your goal. value: BIIB (lower P/E); growth: ALNY (faster 5Y revenue CAGR); quality: ALNY (higher ROIC). Across all compared metrics, they are evenly matched.
Is ALNY or BIIB cheaper?: On trailing earnings, BIIB is cheaper: ALNY trades at a 66.30 P/E and BIIB at 21.12.
Which has grown faster, ALNY or BIIB?: Over the past five years, ALNY grew revenue faster — ALNY at a 49.67% CAGR versus BIIB at -4.80%.
Is ALNY or BIIB more profitable?: BIIB runs the higher net margin — ALNY at 13.46% versus BIIB at 13.92%.
Which has been the better investment, ALNY or BIIB?: Over the past 10-year, ALNY delivered the higher annualized total return — ALNY at 15.78% versus BIIB at -2.74%. Past performance doesn't predict future results.

Go deeper

Full ALNY analysis Full BIIB analysis Interactive comparison tool

Dig into the metrics

Alnylam Pharmaceuticals P/E ratio Biogen P/E ratio Alnylam Pharmaceuticals dividend yield Biogen dividend yield Alnylam Pharmaceuticals ROE Biogen ROE Alnylam Pharmaceuticals operating margin Biogen operating margin Alnylam Pharmaceuticals revenue growth Biogen revenue growth Alnylam Pharmaceuticals free cash flow Biogen free cash flow

Alnylam Pharmaceuticals & Biogen appear in these rankings

Fastest Revenue Growth Stocks Highest ROE Stocks Highest FCF Yield Stocks Best 10-Year Total Return Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified July 16, 2026.