Alkermes plc (ALKS) vs Arrowhead Pharmaceuticals, Inc. (ARWR)
A side-by-side comparison of Alkermes plc and Arrowhead Pharmaceuticals, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
ALKS
Alkermes plc
$41.74HealthcareDelayed quote: Oct 6, 2026, 3:05 PM EDT
ARWR
Arrowhead Pharmaceuticals, Inc.
$62.24HealthcareDelayed quote: Oct 6, 2026, 3:05 PM EDT
Total return — ALKS vs ARWR
growth of $100 · dividends reinvested · last 10yALKS +1.1% (+0.1%/yr)ARWR +839.0% (+25.1%/yr)ARWR compounded faster over this window
Log scale — wide-divergence pair
ALKS ARWR
ALKS vs ARWR: by the numbers
- •ARWR is the larger company ($8.77B vs $7.00B market cap).
- •ALKS is profitable (3.97% net margin) while ARWR runs a net loss (-47.79%).
- •ARWR grew revenue faster over the past five years (44.14% vs 8.68% CAGR).
Metrics side by side
Valuation
| Metric | ALKS | ARWR |
|---|---|---|
| P/E ratio | 108.98 | N/A |
| P/S ratio | 4.20 | 13.09 |
| P/B ratio | 3.87 | 18.83 |
| EV / EBITDA | 45.07 | N/A |
| FCF yield | 3.16% | N/A |
Profitability
| Metric | ALKS | ARWR |
|---|---|---|
| Gross margin | 84.56% | 100.00% |
| Operating margin | 17.21% | 11.86% |
| Net margin | 3.97% | -47.79% |
| ROE | 3.66% | -68.73% |
| ROIC | 2.12% | -12.12% |
Growth (annualized)
| Metric | ALKS | ARWR |
|---|---|---|
| Revenue CAGR (5Y) | 8.68% | 44.14% |
| FCF CAGR (5Y) | 20.00% | N/A |
| Total return CAGR (5Y) | 6.73% | 0.75% |
Frequently asked
- Which has grown faster, ALKS or ARWR?
- Over the past five years, ARWR grew revenue faster — ALKS at a 8.68% CAGR versus ARWR at 44.14%.
- Is ALKS or ARWR more profitable?
- ALKS runs the higher net margin — ALKS at 3.97% versus ARWR at -47.79%.
- How have ALKS and ARWR total returns compared?
- Over the past 10 years, ALKS delivered -0.82% and ARWR delivered 23.56% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Alkermes P/E ratioAlkermes ROEArrowhead Pharmaceuticals ROEAlkermes operating marginArrowhead Pharmaceuticals operating marginAlkermes revenue growthArrowhead Pharmaceuticals revenue growthAlkermes free cash flowArrowhead Pharmaceuticals free cash flow
Alkermes & Arrowhead Pharmaceuticals appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.