Which has the lower trailing P/E, ALKS or AMRX?

AMRX has the lower trailing P/E: ALKS trades at 111.64 and AMRX at 41.74. P/E is one valuation measure and does not by itself establish which business is cheaper.

Is ALKS or AMRX more profitable?

AMRX runs the higher net margin — ALKS at 3.97% versus AMRX at 5.05%.

How have ALKS and AMRX total returns compared?

Over the past 10 years, ALKS delivered -0.82% and AMRX delivered -1.73% annualized total return. Past performance doesn't predict future results.

Alkermes plc (ALKS) vs Amneal Pharmaceuticals, Inc. (AMRX)

A side-by-side comparison of Alkermes plc and Amneal Pharmaceuticals, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

ALKS

Alkermes plc

$7.17B

$42.76HealthcareDelayed quote: Oct 5, 2026, 4:00 PM EDT

AMRX

Amneal Pharmaceuticals, Inc.

$6.50B

$20.35HealthcareDelayed quote: Oct 5, 2026, 4:00 PM EDT

Total return — ALKS vs AMRX

growth of $100 · dividends reinvested · last 10y

ALKS -7.3% (-0.8%/yr)AMRX -13.6% (-1.5%/yr)ALKS compounded faster over this window

ALKS AMRX

ALKS vs AMRX: by the numbers

•ALKS is the larger company ($7.17B vs $6.50B market cap).
•AMRX trades at the lower trailing earnings multiple (41.74 vs 111.64 P/E), one valuation lens rather than an overall verdict.
•AMRX converts more revenue to profit (5.05% vs 3.97% net margin).

Metrics side by side

Valuation

Metric	ALKS	AMRX
P/E ratio	111.64	41.74
Forward P/E	N/A	19.88
P/S ratio	4.30	2.08
P/B ratio	3.97	196.78
EV / EBITDA	46.03	15.33
FCF yield	3.09%	1.28%

Profitability

Metric	ALKS	AMRX
Gross margin	84.56%	39.32%
Operating margin	17.21%	12.93%
Net margin	3.97%	5.05%
ROE	3.66%	476.51%
ROIC	2.12%	13.45%

Growth (annualized)

Metric	ALKS	AMRX
Revenue CAGR (5Y)	8.68%	8.67%
EPS CAGR (5Y)	N/A	-17.72%
FCF CAGR (5Y)	20.00%	-14.46%
Total return CAGR (5Y)	6.73%	30.25%

Frequently asked

Which has the lower trailing P/E, ALKS or AMRX?: AMRX has the lower trailing P/E: ALKS trades at 111.64 and AMRX at 41.74. P/E is one valuation measure and does not by itself establish which business is cheaper.
Is ALKS or AMRX more profitable?: AMRX runs the higher net margin — ALKS at 3.97% versus AMRX at 5.05%.
How have ALKS and AMRX total returns compared?: Over the past 10 years, ALKS delivered -0.82% and AMRX delivered -1.73% annualized total return. Past performance doesn't predict future results.

Go deeper

Full ALKS analysis Full AMRX analysis Interactive comparison tool

Dig into the metrics

Alkermes P/E ratio Amneal Pharmaceuticals P/E ratio Alkermes ROE Amneal Pharmaceuticals ROE Alkermes operating margin Amneal Pharmaceuticals operating margin Alkermes revenue growth Amneal Pharmaceuticals revenue growth Alkermes free cash flow Amneal Pharmaceuticals free cash flow

Alkermes & Amneal Pharmaceuticals appear in these rankings

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Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.