Which has grown faster, ALGN or TXG?

Over the past five years, TXG grew revenue faster — ALGN at a 3.57% CAGR versus TXG at 8.74%.

Is ALGN or TXG more profitable?

ALGN runs the higher net margin — ALGN at 9.99% versus TXG at -12.18%.

How have ALGN and TXG total returns compared?

Over the past 5 years, ALGN delivered -26.34% and TXG delivered -7.24% annualized total return. Past performance doesn't predict future results.

Align Technology, Inc. (ALGN) vs 10x Genomics, Inc. (TXG)

A side-by-side comparison of Align Technology, Inc. and 10x Genomics, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 5, 2026. Differences are shown without an overall score or investment verdict.

ALGN

Align Technology, Inc.

$10.21B

$142.51HealthcareDelayed quote: Oct 6, 2026, 3:10 PM EDT

TXG

10x Genomics, Inc.

$10.19B

$80.28HealthcareDelayed quote: Oct 6, 2026, 3:05 PM EDT

Total return — ALGN vs TXG

growth of $100 · dividends reinvested · last 7y

ALGN -19.5% (-3.0%/yr)TXG +85.3% (+9.2%/yr)TXG compounded faster over this window

ALGN TXG

ALGN vs TXG: by the numbers

•ALGN is the larger company ($10.21B vs $10.19B market cap).
•ALGN is profitable (9.99% net margin) while TXG runs a net loss (-12.18%).
•TXG grew revenue faster over the past five years (8.74% vs 3.57% CAGR).

Metrics side by side

Valuation

Metric	ALGN	TXG
P/E ratio	24.74	N/A
Forward P/E	12.62	N/A
P/S ratio	2.47	16.52
P/B ratio	2.41	12.35
EV / EBITDA	11.44	N/A
FCF yield	N/A	1.19%

Profitability

Metric	ALGN	TXG
Gross margin	66.48%	70.03%
Operating margin	13.33%	-14.33%
Net margin	9.99%	-12.18%
ROE	9.77%	-9.10%
ROIC	8.90%	-9.57%

Growth (annualized)

Metric	ALGN	TXG
Revenue CAGR (5Y)	3.57%	8.74%
EPS CAGR (5Y)	-24.16%	N/A
Total return CAGR (5Y)	-26.34%	-7.24%

Some values include inputs from SEC filing.

Frequently asked

Which has grown faster, ALGN or TXG?: Over the past five years, TXG grew revenue faster — ALGN at a 3.57% CAGR versus TXG at 8.74%.
Is ALGN or TXG more profitable?: ALGN runs the higher net margin — ALGN at 9.99% versus TXG at -12.18%.
How have ALGN and TXG total returns compared?: Over the past 5 years, ALGN delivered -26.34% and TXG delivered -7.24% annualized total return. Past performance doesn't predict future results.

Go deeper

Full ALGN analysis Full TXG analysis Interactive comparison tool

Dig into the metrics

Align Technology P/E ratio Align Technology ROE 10x Genomics ROE Align Technology operating margin 10x Genomics operating margin Align Technology revenue growth 10x Genomics revenue growth Align Technology free cash flow 10x Genomics free cash flow

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 5, 2026.