Align Technology, Inc. (ALGN) vs Tempus AI, Inc. (TEM)
A side-by-side comparison of Align Technology, Inc. and Tempus AI, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of August 19, 2026. Differences are shown without an overall score or investment verdict.
ALGN
Align Technology, Inc.
$163.04HealthcareDelayed quote: Aug 19, 2026, 4:00 PM EDT
TEM
Tempus AI, Inc.
$61.25HealthcareDelayed quote: Aug 19, 2026, 4:00 PM EDT
Total return — ALGN vs TEM
growth of $100 · dividends reinvested · last 2yALGN -32.4% (-17.8%/yr)TEM +22.6% (+10.7%/yr)TEM compounded faster over this window
ALGN TEM
ALGN vs TEM: by the numbers
- •ALGN is the larger company ($11.68B vs $10.73B market cap).
- •ALGN is profitable (9.99% net margin) while TEM runs a net loss (-17.77%).
- •TEM grew revenue faster over the past five years (38.24% vs 3.57% CAGR).
Metrics side by side
Valuation
| Metric | ALGN | TEM |
|---|---|---|
| P/E ratio | 28.31 | N/A |
| Forward P/E | 14.45 | N/A |
| P/S ratio | 2.82 | 6.29 |
| P/B ratio | 2.76 | 20.23 |
| EV / EBITDA | 15.08 | N/A |
| FCF yield | 6.47% | N/A |
Profitability
| Metric | ALGN | TEM |
|---|---|---|
| Gross margin | 66.48% | 63.98% |
| Operating margin | 13.33% | -19.76% |
| Net margin | 9.99% | -17.77% |
| ROE | 9.77% | -57.18% |
| ROIC | 8.90% | -14.34% |
Growth (annualized)
| Metric | ALGN | TEM |
|---|---|---|
| Revenue CAGR (5Y) | 3.57% | 38.24% |
| EPS CAGR (5Y) | -24.16% | N/A |
| FCF CAGR (5Y) | -3.33% | N/A |
| Total return CAGR (5Y) | -24.84% | N/A |
Frequently asked
- Which has grown faster, ALGN or TEM?
- Over the past five years, TEM grew revenue faster — ALGN at a 3.57% CAGR versus TEM at 38.24%.
- Is ALGN or TEM more profitable?
- ALGN runs the higher net margin — ALGN at 9.99% versus TEM at -17.77%.
Go deeper
Dig into the metrics
Align Technology P/E ratioAlign Technology ROETempus AI ROEAlign Technology operating marginTempus AI operating marginAlign Technology revenue growthTempus AI revenue growthAlign Technology free cash flowTempus AI free cash flow
Align Technology & Tempus AI appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified August 19, 2026.