Which has the lower trailing P/E, ALGN or HOLX?

ALGN has the lower trailing P/E: ALGN trades at 30.11 and HOLX at 31.67. P/E is one valuation measure and does not by itself establish which business is cheaper.

Which has grown faster, ALGN or HOLX?

Over the past five years, ALGN grew revenue faster — ALGN at a 3.57% CAGR versus HOLX at 1.66%.

Is ALGN or HOLX more profitable?

HOLX runs the higher net margin — ALGN at 9.99% versus HOLX at 13.18%.

How have ALGN and HOLX total returns compared?

Over the past 10 years, ALGN delivered 6.88% and HOLX delivered 7.99% annualized total return. Past performance doesn't predict future results.

Align Technology, Inc. (ALGN) vs Hologic, Inc. (HOLX)

A side-by-side comparison of Align Technology, Inc. and Hologic, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of July 31, 2026. Differences are shown without an overall score or investment verdict.

ALGN

Align Technology, Inc.

$12.16B

$169.74HealthcareDelayed quote: Jul 31, 2026, 2:35 PM EDT

HOLX

Hologic, Inc.

$16.97B

$76.01HealthcareAt close: Apr 7, 2026, 4:00 PM ET

Total return — ALGN vs HOLX

growth of $100 · dividends reinvested · last 25y

ALGN +915.9%HOLX +4243.4%HOLX compounded faster

ALGN HOLX

ALGN vs HOLX: by the numbers

•HOLX is the larger company ($16.97B vs $12.16B market cap).
•ALGN trades at the lower trailing earnings multiple (30.11 vs 31.67 P/E), one valuation lens rather than an overall verdict.
•HOLX converts more revenue to profit (13.18% vs 9.99% net margin).
•ALGN grew revenue faster over the past five years (3.57% vs 1.66% CAGR).

Metrics side by side

Valuation

Metric	ALGN	HOLX
P/E ratio	30.11	31.67
Forward P/E	15.27	17.21
P/S ratio	3.00	4.16
P/B ratio	2.93	3.27
PEG ratio	51.77	N/A
EV / EBITDA	16.07	17.99
FCF yield	6.08%	5.82%

Profitability

Metric	ALGN	HOLX
Gross margin	68.16%	61.00%
Operating margin	13.33%	17.49%
Net margin	9.99%	13.18%
ROE	9.77%	10.37%
ROIC	9.94%	7.35%

Growth (annualized)

Metric	ALGN	HOLX
Revenue CAGR (5Y)	3.57%	1.66%
EPS CAGR (5Y)	-24.16%	-0.96%
FCF CAGR (5Y)	-3.33%	4.46%
Total return CAGR (5Y)	-24.26%	0.84%

Frequently asked

Which has the lower trailing P/E, ALGN or HOLX?: ALGN has the lower trailing P/E: ALGN trades at 30.11 and HOLX at 31.67. P/E is one valuation measure and does not by itself establish which business is cheaper.
Which has grown faster, ALGN or HOLX?: Over the past five years, ALGN grew revenue faster — ALGN at a 3.57% CAGR versus HOLX at 1.66%.
Is ALGN or HOLX more profitable?: HOLX runs the higher net margin — ALGN at 9.99% versus HOLX at 13.18%.
How have ALGN and HOLX total returns compared?: Over the past 10 years, ALGN delivered 6.88% and HOLX delivered 7.99% annualized total return. Past performance doesn't predict future results.

Go deeper

Full ALGN analysis Full HOLX analysis Interactive comparison tool

Dig into the metrics

Align Technology P/E ratio Hologic P/E ratio Align Technology dividend yield Hologic dividend yield Align Technology ROE Hologic ROE Align Technology operating margin Hologic operating margin Align Technology revenue growth Hologic revenue growth Align Technology free cash flow Hologic free cash flow

Align Technology & Hologic appear in these rankings

Highest FCF Yield Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified July 31, 2026.