Align Technology, Inc. (ALGN) vs Hologic, Inc. (HOLX)

ALGN leads on 9 of 14 compared metrics.

A side-by-side comparison of Align Technology, Inc. and Hologic, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of June 13, 2026. The ● marks the stronger figure on each row (cheaper multiple, higher margin/return).

Total return — ALGN vs HOLX

growth of $100 · last 25y
ALGN +888.9%HOLX +4205.0%HOLX compounded faster
01k2k3k4k5kStart $10020062011201620212026$989$4,305
ALGN HOLX

ALGN vs HOLX: by the numbers

  • HOLX is the larger company ($16.97B vs $12.52B market cap).
  • ALGN trades at the lower earnings multiple (29.34 vs 31.67 P/E).
  • HOLX converts more revenue to profit (13.18% vs 10.50% net margin).
  • ALGN grew revenue faster over the past five years (7.78% vs -1.87% CAGR).

Which is better, ALGN or HOLX?

Metric tally: ALGN 9 · HOLX 5

It depends on what you're optimizing for:

ValueALGN(lower P/E)
GrowthALGN(faster 5Y revenue CAGR)
QualityALGN(higher ROIC)

Valuation

MetricALGNHOLX
P/E ratio29.3431.67
Forward P/E15.3717.21
P/S ratio3.064.16
P/B ratio3.023.27
PEG ratio51.80
EV / EBITDA14.5517.28
FCF yield5.48%5.82%

Profitability

MetricALGNHOLX
Gross margin67.68%52.82%
Operating margin14.44%17.49%
Net margin10.50%13.18%
ROE10.36%10.37%
ROIC9.94%7.35%

Growth (annualized)

MetricALGNHOLX
Revenue CAGR (5Y)7.78%-1.87%
EPS CAGR (5Y)-24.16%-0.96%
FCF CAGR (5Y)-1.16%-4.57%
Total return CAGR (5Y)-22.14%0.84%

Frequently asked

Which is better, ALGN or HOLX?
It depends on your goal. value: ALGN (lower P/E); growth: ALGN (faster 5Y revenue CAGR); quality: ALGN (higher ROIC). Across all compared metrics, ALGN leads 9 to 5.
Is ALGN or HOLX cheaper?
On trailing earnings, ALGN is cheaper: ALGN trades at a 29.34 P/E and HOLX at 31.67.
Which has grown faster, ALGN or HOLX?
Over the past five years, ALGN grew revenue faster — ALGN at a 7.78% CAGR versus HOLX at -1.87%.
Is ALGN or HOLX more profitable?
HOLX runs the higher net margin — ALGN at 10.50% versus HOLX at 13.18%.
Which has been the better investment, ALGN or HOLX?
Over the past 10-year, ALGN delivered the higher annualized total return — ALGN at 8.29% versus HOLX at 7.99%. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified June 13, 2026.