Which has the lower trailing P/E, ALGN or BMRN?

ALGN has the lower trailing P/E: ALGN trades at 24.79 and BMRN at 145.51. P/E is one valuation measure and does not by itself establish which business is cheaper.

Which has grown faster, ALGN or BMRN?

Over the past five years, BMRN grew revenue faster — ALGN at a 3.57% CAGR versus BMRN at 12.19%.

Is ALGN or BMRN more profitable?

ALGN runs the higher net margin — ALGN at 9.99% versus BMRN at 2.14%.

How have ALGN and BMRN total returns compared?

Over the past 10 years, ALGN delivered 4.63% and BMRN delivered -4.98% annualized total return. Past performance doesn't predict future results.

Align Technology, Inc. (ALGN) vs BioMarin Pharmaceutical Inc. (BMRN)

A side-by-side comparison of Align Technology, Inc. and BioMarin Pharmaceutical Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 5, 2026. Differences are shown without an overall score or investment verdict.

ALGN

Align Technology, Inc.

$10.23B

$142.82HealthcareDelayed quote: Oct 6, 2026, 12:15 PM EDT

BMRN

BioMarin Pharmaceutical Inc.

$10.97B

$56.75HealthcareDelayed quote: Oct 6, 2026, 12:10 PM EDT

Total return — ALGN vs BMRN

growth of $100 · dividends reinvested · last 10y

ALGN +54.4% (+4.4%/yr)BMRN -39.5% (-4.9%/yr)ALGN compounded faster over this window

ALGN BMRN

ALGN vs BMRN: by the numbers

•BMRN is the larger company ($10.97B vs $10.23B market cap).
•ALGN trades at the lower trailing earnings multiple (24.79 vs 145.51 P/E), one valuation lens rather than an overall verdict.
•ALGN converts more revenue to profit (9.99% vs 2.14% net margin).
•BMRN grew revenue faster over the past five years (12.19% vs 3.57% CAGR).

Metrics side by side

Valuation

Metric	ALGN	BMRN
P/E ratio	24.79	145.51
Forward P/E	12.65	N/A
P/S ratio	2.47	3.22
P/B ratio	2.42	1.74
EV / EBITDA	11.47	33.54
FCF yield	N/A	6.68%

Profitability

Metric	ALGN	BMRN
Gross margin	66.48%	75.55%
Operating margin	13.33%	16.56%
Net margin	9.99%	2.14%
ROE	9.77%	1.15%
ROIC	8.90%	1.40%

Growth (annualized)

Metric	ALGN	BMRN
Revenue CAGR (5Y)	3.57%	12.19%
EPS CAGR (5Y)	-24.16%	-17.46%
FCF CAGR (5Y)	N/A	33.84%
Total return CAGR (5Y)	-26.34%	-5.59%

Some values include inputs from SEC filing.

Frequently asked

Which has the lower trailing P/E, ALGN or BMRN?: ALGN has the lower trailing P/E: ALGN trades at 24.79 and BMRN at 145.51. P/E is one valuation measure and does not by itself establish which business is cheaper.
Which has grown faster, ALGN or BMRN?: Over the past five years, BMRN grew revenue faster — ALGN at a 3.57% CAGR versus BMRN at 12.19%.
Is ALGN or BMRN more profitable?: ALGN runs the higher net margin — ALGN at 9.99% versus BMRN at 2.14%.
How have ALGN and BMRN total returns compared?: Over the past 10 years, ALGN delivered 4.63% and BMRN delivered -4.98% annualized total return. Past performance doesn't predict future results.

Go deeper

Full ALGN analysis Full BMRN analysis Interactive comparison tool

Dig into the metrics

Align Technology P/E ratio BioMarin Pharmaceutical P/E ratio Align Technology ROE BioMarin Pharmaceutical ROE Align Technology operating margin BioMarin Pharmaceutical operating margin Align Technology revenue growth BioMarin Pharmaceutical revenue growth Align Technology free cash flow BioMarin Pharmaceutical free cash flow

Align Technology & BioMarin Pharmaceutical appear in these rankings

Highest FCF Yield Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 5, 2026.