Which has the lower trailing P/E, ALGN or BIO?

ALGN has the lower trailing P/E: ALGN trades at 24.95 and BIO at 44.74. P/E is one valuation measure and does not by itself establish which business is cheaper.

Which has grown faster, ALGN or BIO?

Over the past five years, ALGN grew revenue faster — ALGN at a 3.57% CAGR versus BIO at 0.29%.

Is ALGN or BIO more profitable?

ALGN runs the higher net margin — ALGN at 9.99% versus BIO at 8.59%.

How have ALGN and BIO total returns compared?

Over the past 10 years, ALGN delivered 4.36% and BIO delivered 8.46% annualized total return. Past performance doesn't predict future results.

Align Technology, Inc. (ALGN) vs Bio-Rad Laboratories, Inc. (BIO)

A side-by-side comparison of Align Technology, Inc. and Bio-Rad Laboratories, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 4, 2026. Differences are shown without an overall score or investment verdict.

ALGN

Align Technology, Inc.

$10.29B

$143.74HealthcareDelayed quote: Oct 2, 2026, 4:00 PM EDT

BIO

Bio-Rad Laboratories, Inc.

$9.94B

$369.14HealthcareDelayed quote: Oct 2, 2026, 4:00 PM EDT

Total return — ALGN vs BIO

growth of $100 · dividends reinvested · last 10y

ALGN +57.8% (+4.7%/yr)BIO +127.9% (+8.6%/yr)BIO compounded faster over this window

ALGN BIO

ALGN vs BIO: by the numbers

•ALGN is the larger company ($10.29B vs $9.94B market cap).
•ALGN trades at the lower trailing earnings multiple (24.95 vs 44.74 P/E), one valuation lens rather than an overall verdict.
•ALGN converts more revenue to profit (9.99% vs 8.59% net margin).
•ALGN grew revenue faster over the past five years (3.57% vs 0.29% CAGR).

Metrics side by side

Valuation

Metric	ALGN	BIO
P/E ratio	24.95	44.74
Forward P/E	12.73	38.07
P/S ratio	2.49	3.84
P/B ratio	2.43	1.39
EV / EBITDA	11.55	27.77
FCF yield	N/A	3.55%

Profitability

Metric	ALGN	BIO
Gross margin	66.48%	51.90%
Operating margin	13.33%	9.08%
Net margin	9.99%	8.59%
ROE	9.77%	3.10%
ROIC	8.90%	1.54%

Growth (annualized)

Metric	ALGN	BIO
Revenue CAGR (5Y)	3.57%	0.29%
EPS CAGR (5Y)	-24.16%	-26.27%
FCF CAGR (5Y)	N/A	-9.65%
Total return CAGR (5Y)	-26.31%	-13.03%

Some values include inputs from SEC filing.

Frequently asked

Which has the lower trailing P/E, ALGN or BIO?: ALGN has the lower trailing P/E: ALGN trades at 24.95 and BIO at 44.74. P/E is one valuation measure and does not by itself establish which business is cheaper.
Which has grown faster, ALGN or BIO?: Over the past five years, ALGN grew revenue faster — ALGN at a 3.57% CAGR versus BIO at 0.29%.
Is ALGN or BIO more profitable?: ALGN runs the higher net margin — ALGN at 9.99% versus BIO at 8.59%.
How have ALGN and BIO total returns compared?: Over the past 10 years, ALGN delivered 4.36% and BIO delivered 8.46% annualized total return. Past performance doesn't predict future results.

Go deeper

Full ALGN analysis Full BIO analysis Interactive comparison tool

Dig into the metrics

Align Technology P/E ratio Bio-Rad Laboratories P/E ratio Align Technology ROE Bio-Rad Laboratories ROE Align Technology operating margin Bio-Rad Laboratories operating margin Align Technology revenue growth Bio-Rad Laboratories revenue growth Align Technology free cash flow Bio-Rad Laboratories free cash flow

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 4, 2026.