Alector, Inc. (ALEC) vs Sionna Therapeutics, Inc. (SION)
A side-by-side comparison of Alector, Inc. and Sionna Therapeutics, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
ALEC
Alector, Inc.
$1.85HealthcareDelayed quote: Oct 6, 2026, 1:50 PM EDT
SION
Sionna Therapeutics, Inc.
$4.56HealthcareDelayed quote: Oct 6, 2026, 1:50 PM EDT
Total return — ALEC vs SION
growth of $100 · dividends reinvested · last 2yALEC +11.2% (+5.4%/yr)SION -80.6% (-56.0%/yr)ALEC compounded faster over this window
Log scale — wide-divergence pair
ALEC SION
ALEC vs SION: by the numbers
- •SION is the larger company ($206M vs $205M market cap).
- •Both run net losses; SION's is the smaller (0.00% vs -850.13% net margin).
Metrics side by side
Valuation
| Metric | ALEC | SION |
|---|---|---|
| P/S ratio | 14.82 | N/A |
| P/B ratio | N/A | 0.77 |
Profitability
| Metric | ALEC | SION |
|---|---|---|
| Gross margin | 54.09% | 0.00% |
| Operating margin | -692.83% | 0.00% |
| Net margin | -850.13% | 0.00% |
| ROE | N/A | -36.64% |
| ROIC | -71.04% | -40.18% |
Growth (annualized)
| Metric | ALEC | SION |
|---|---|---|
| Revenue CAGR (5Y) | -8.35% | N/A |
| Total return CAGR (5Y) | -39.17% | N/A |
Go deeper
Dig into the metrics
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.