Alector, Inc. (ALEC) vs Prelude Therapeutics Incorporated (PRLD)
A side-by-side comparison of Alector, Inc. and Prelude Therapeutics Incorporated across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
ALEC
Alector, Inc.
$1.81HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT
PRLD
Prelude Therapeutics Incorporated
$3.81HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT
Total return — ALEC vs PRLD
growth of $100 · dividends reinvested · last 6yALEC -82.4% (-25.1%/yr)PRLD -85.6% (-27.6%/yr)ALEC compounded faster over this window
ALEC PRLD
ALEC vs PRLD: by the numbers
- •PRLD is the larger company ($217M vs $201M market cap).
- •Both run net losses; PRLD's is the smaller (-269.75% vs -850.13% net margin).
Metrics side by side
Valuation
| Metric | ALEC | PRLD |
|---|---|---|
| P/S ratio | 14.50 | 9.67 |
| P/B ratio | N/A | 1.62 |
Profitability
| Metric | ALEC | PRLD |
|---|---|---|
| Gross margin | 54.09% | 85.91% |
| Operating margin | -692.83% | -861.33% |
| Net margin | -850.13% | -269.75% |
| ROE | N/A | -45.23% |
| ROIC | -71.04% | -43.74% |
Growth (annualized)
| Metric | ALEC | PRLD |
|---|---|---|
| Revenue CAGR (5Y) | -8.35% | N/A |
| Total return CAGR (5Y) | -39.17% | -33.98% |
Frequently asked
- How have ALEC and PRLD total returns compared?
- Over the past 5 years, ALEC delivered -39.17% and PRLD delivered -33.98% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.