Which has the lower trailing P/E, ALC or ALNY?

ALNY has the lower trailing P/E: ALC trades at 55.56 and ALNY at 39.96. P/E is one valuation measure and does not by itself establish which business is cheaper.

Which has grown faster, ALC or ALNY?

Over the past five years, ALNY grew revenue faster — ALC at a 6.57% CAGR versus ALNY at 47.53%.

Does ALC or ALNY pay a bigger dividend?

ALC pays a dividend (0.50% yield), while ALNY has no payments in the available dividend history.

Is ALC or ALNY more profitable?

ALNY runs the higher net margin — ALC at 5.95% versus ALNY at 16.82%.

How have ALC and ALNY total returns compared?

Over the past 5 years, ALC delivered -2.16% and ALNY delivered 12.82% annualized total return. Past performance doesn't predict future results.

Alcon Inc. (ALC) vs Alnylam Pharmaceuticals, Inc. (ALNY)

A side-by-side comparison of Alcon Inc. and Alnylam Pharmaceuticals, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of August 28, 2026. Differences are shown without an overall score or investment verdict.

ALC

Alcon Inc.

$34.86B

$71.47HealthcareDelayed quote: Aug 28, 2026, 12:44 PM EDT

ALNY

Alnylam Pharmaceuticals, Inc.

$31.37B

$234.45HealthcareDelayed quote: Aug 28, 2026, 12:45 PM EDT

Total return — ALC vs ALNY

growth of $100 · dividends reinvested · last 7y

ALC +26.9% (+3.5%/yr)ALNY +154.9% (+14.3%/yr)ALNY compounded faster over this window

ALC ALNY

ALC vs ALNY: by the numbers

•ALC is the larger company ($34.86B vs $31.37B market cap).
•ALNY trades at the lower trailing earnings multiple (39.96 vs 55.56 P/E), one valuation lens rather than an overall verdict.
•ALNY converts more revenue to profit (16.82% vs 5.95% net margin).
•ALNY grew revenue faster over the past five years (47.53% vs 6.57% CAGR).
•ALC pays a dividend (0.50% yield), while ALNY has no payments in the available dividend history.

Metrics side by side

Valuation

Metric	ALC	ALNY
P/E ratio	55.56	39.96
Forward P/E	20.49	36.35
P/S ratio	3.28	6.81
P/B ratio	1.63	24.15
EV / EBITDA	17.44	30.60
FCF yield	4.77%	1.66%

Profitability

Metric	ALC	ALNY
Gross margin	56.43%	79.72%
Operating margin	10.26%	20.81%
Net margin	5.95%	16.82%
ROE	2.96%	59.67%
ROIC	3.35%	24.71%

Dividends

Metric	ALC	ALNY
Dividend yield	0.50%	N/A
Payout ratio	18.06%	N/A

Growth (annualized)

Metric	ALC	ALNY
Revenue CAGR (5Y)	6.57%	47.53%
FCF CAGR (5Y)	40.55%	N/A
Total return CAGR (5Y)	-2.16%	3.01%

Frequently asked

Which has the lower trailing P/E, ALC or ALNY?: ALNY has the lower trailing P/E: ALC trades at 55.56 and ALNY at 39.96. P/E is one valuation measure and does not by itself establish which business is cheaper.
Which has grown faster, ALC or ALNY?: Over the past five years, ALNY grew revenue faster — ALC at a 6.57% CAGR versus ALNY at 47.53%.
Does ALC or ALNY pay a bigger dividend?: ALC pays a dividend (0.50% yield), while ALNY has no payments in the available dividend history.
Is ALC or ALNY more profitable?: ALNY runs the higher net margin — ALC at 5.95% versus ALNY at 16.82%.
How have ALC and ALNY total returns compared?: Over the past 5 years, ALC delivered -2.16% and ALNY delivered 12.82% annualized total return. Past performance doesn't predict future results.

Go deeper

Full ALC analysis Full ALNY analysis Interactive comparison tool

Dig into the metrics

Alcon P/E ratio Alnylam Pharmaceuticals P/E ratio Alcon dividend yield Alcon ROE Alnylam Pharmaceuticals ROE Alcon operating margin Alnylam Pharmaceuticals operating margin Alcon revenue growth Alnylam Pharmaceuticals revenue growth Alcon free cash flow Alnylam Pharmaceuticals free cash flow

Alcon & Alnylam Pharmaceuticals appear in these rankings

Fastest Revenue Growth Stocks Highest ROE Stocks Highest ROIC Stocks Highest FCF Yield Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified August 28, 2026.