Akebia Therapeutics, Inc. (AKBA) vs Alector, Inc. (ALEC)
A side-by-side comparison of Akebia Therapeutics, Inc. and Alector, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
AKBA
Akebia Therapeutics, Inc.
$0.90HealthcareDelayed quote: Oct 6, 2026, 12:00 PM EDT
ALEC
Alector, Inc.
$1.96HealthcareDelayed quote: Oct 6, 2026, 12:00 PM EDT
Total return — AKBA vs ALEC
growth of $100 · dividends reinvested · last 8yAKBA -84.6% (-20.8%/yr)ALEC -88.9% (-24.1%/yr)AKBA compounded faster over this window
AKBA ALEC
AKBA vs ALEC: by the numbers
- •AKBA is the larger company ($241M vs $218M market cap).
- •Both run net losses; AKBA's is the smaller (-13.54% vs -850.13% net margin).
- •Both shrank revenue over the past five years; AKBA's decline was smaller (-0.26% vs -8.35% CAGR).
Metrics side by side
Valuation
| Metric | AKBA | ALEC |
|---|---|---|
| P/S ratio | 1.10 | 15.70 |
| P/B ratio | 9.63 | N/A |
| FCF yield | 16.68% | N/A |
Profitability
| Metric | AKBA | ALEC |
|---|---|---|
| Gross margin | 79.48% | 54.09% |
| Operating margin | 9.95% | -692.83% |
| Net margin | -13.54% | -850.13% |
| ROE | -118.58% | N/A |
| ROIC | -7.08% | -71.04% |
Growth (annualized)
| Metric | AKBA | ALEC |
|---|---|---|
| Revenue CAGR (5Y) | -0.26% | -8.35% |
| Total return CAGR (5Y) | -20.07% | -39.17% |
Frequently asked
- Which has grown faster, AKBA or ALEC?
- Neither grew: over the past five years both shrank revenue, with AKBA's decline the smaller — AKBA at a -0.26% CAGR versus ALEC at -8.35%.
- How have AKBA and ALEC total returns compared?
- Over the past 5 years, AKBA delivered -20.07% and ALEC delivered -39.17% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Akebia Therapeutics ROEAlector ROEAkebia Therapeutics operating marginAlector operating marginAkebia Therapeutics revenue growthAlector revenue growthAkebia Therapeutics free cash flowAlector free cash flow
Akebia Therapeutics & Alector appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.