Agenus Inc. (AGEN) vs Enanta Pharmaceuticals, Inc. (ENTA)

A side-by-side comparison of Agenus Inc. and Enanta Pharmaceuticals, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

Compare

Total return — AGEN vs ENTA

growth of $100 · dividends reinvested · last 10y
AGEN -94.1% (-24.6%/yr)ENTA -52.4% (-7.2%/yr)ENTA compounded faster over this window
Log scale — wide-divergence pair
1101001kStart $10020182020202220242026$6$48
AGEN ENTA

AGEN vs ENTA: by the numbers

  • •ENTA is the larger company ($366M vs $354M market cap).
  • •AGEN is profitable (69.34% net margin) while ENTA runs a net loss (-96.89%).
  • •AGEN grew revenue faster over the past five years (14.13% vs -7.65% CAGR).

Metrics side by side

Valuation

MetricAGENENTA
P/E ratio3.21N/A
Forward P/E31.74N/A
P/S ratio2.665.61
P/B ratioN/A3.63
EV / EBITDA9.17N/A

Profitability

MetricAGENENTA
Gross margin29.63%98.15%
Operating margin-18.00%-130.65%
Net margin69.34%-96.89%
ROEN/A-62.56%
ROICN/A-24.20%

Growth (annualized)

MetricAGENENTA
Revenue CAGR (5Y)14.13%-7.65%
Total return CAGR (5Y)-40.10%-26.94%

Frequently asked

Which has grown faster, AGEN or ENTA?
Over the past five years, AGEN grew revenue faster — AGEN at a 14.13% CAGR versus ENTA at -7.65%.
Is AGEN or ENTA more profitable?
AGEN runs the higher net margin — AGEN at 69.34% versus ENTA at -96.89%.
How have AGEN and ENTA total returns compared?
Over the past 10 years, AGEN delivered -24.61% and ENTA delivered -7.11% annualized total return. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.