Which has grown faster, AGEN or CLPT?

Over the past five years, CLPT grew revenue faster — AGEN at a 14.13% CAGR versus CLPT at 23.57%.

Is AGEN or CLPT more profitable?

AGEN runs the higher net margin — AGEN at 69.34% versus CLPT at -81.76%.

How have AGEN and CLPT total returns compared?

Over the past 10 years, AGEN delivered -24.61% and CLPT delivered 6.57% annualized total return. Past performance doesn't predict future results.

Agenus Inc. (AGEN) vs ClearPoint Neuro, Inc. (CLPT)

A side-by-side comparison of Agenus Inc. and ClearPoint Neuro, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

AGEN

Agenus Inc.

$330M

$7.93HealthcareDelayed quote: Oct 6, 2026, 12:45 PM EDT

CLPT

ClearPoint Neuro, Inc.

$323M

$10.77HealthcareDelayed quote: Oct 6, 2026, 12:45 PM EDT

Total return — AGEN vs CLPT

growth of $100 · dividends reinvested · last 10y

AGEN -94.1% (-24.6%/yr)CLPT +88.9% (+6.6%/yr)CLPT compounded faster over this window

Log scale — wide-divergence pair

AGEN CLPT

AGEN vs CLPT: by the numbers

•AGEN is the larger company ($330M vs $323M market cap).
•AGEN is profitable (69.34% net margin) while CLPT runs a net loss (-81.76%).
•CLPT grew revenue faster over the past five years (23.57% vs 14.13% CAGR).

Metrics side by side

Valuation

Metric	AGEN	CLPT
P/E ratio	3.00	N/A
Forward P/E	29.63	N/A
P/S ratio	2.49	7.64
P/B ratio	N/A	29.97
EV / EBITDA	8.60	N/A

Profitability

Metric	AGEN	CLPT
Gross margin	29.63%	62.61%
Operating margin	-18.00%	-65.36%
Net margin	69.34%	-81.76%
ROE	N/A	-320.77%
ROIC	N/A	-40.51%

Growth (annualized)

Metric	AGEN	CLPT
Revenue CAGR (5Y)	14.13%	23.57%
Total return CAGR (5Y)	-40.10%	-7.65%

Frequently asked

Which has grown faster, AGEN or CLPT?: Over the past five years, CLPT grew revenue faster — AGEN at a 14.13% CAGR versus CLPT at 23.57%.
Is AGEN or CLPT more profitable?: AGEN runs the higher net margin — AGEN at 69.34% versus CLPT at -81.76%.
How have AGEN and CLPT total returns compared?: Over the past 10 years, AGEN delivered -24.61% and CLPT delivered 6.57% annualized total return. Past performance doesn't predict future results.

Go deeper

Full AGEN analysis Full CLPT analysis Interactive comparison tool

Dig into the metrics

Agenus P/E ratio Agenus ROE ClearPoint Neuro ROE Agenus operating margin ClearPoint Neuro operating margin Agenus revenue growth ClearPoint Neuro revenue growth Agenus free cash flow ClearPoint Neuro free cash flow

Agenus & ClearPoint Neuro appear in these rankings

Fastest Revenue Growth Stocks Lowest P/E Ratio Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.