Is AGEN or BNTC more profitable?

AGEN runs the higher net margin — AGEN at 69.34% versus BNTC at 0.00%.

How have AGEN and BNTC total returns compared?

Over the past 10 years, AGEN delivered -24.61% and BNTC delivered -30.49% annualized total return. Past performance doesn't predict future results.

Agenus Inc. (AGEN) vs Benitec Biopharma Inc. (BNTC)

A side-by-side comparison of Agenus Inc. and Benitec Biopharma Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

AGEN

Agenus Inc.

$312M

$7.49HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT

BNTC

Benitec Biopharma Inc.

$309M

$9.00HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT

Total return — AGEN vs BNTC

growth of $100 · dividends reinvested · last 10y

AGEN -94.1% (-24.6%/yr)BNTC -97.4% (-30.5%/yr)AGEN compounded faster over this window

AGEN BNTC

AGEN vs BNTC: by the numbers

•AGEN is the larger company ($312M vs $309M market cap).
•AGEN is profitable (69.34% net margin) while BNTC runs a net loss (0.00%).

Metrics side by side

Valuation

Metric	AGEN	BNTC
P/E ratio	2.83	N/A
Forward P/E	28.00	N/A
P/S ratio	2.35	N/A
P/B ratio	N/A	1.75
EV / EBITDA	8.16	N/A

Profitability

Metric	AGEN	BNTC
Gross margin	29.63%	0.00%
Operating margin	-18.00%	0.00%
Net margin	69.34%	0.00%
ROE	N/A	-25.73%
ROIC	N/A	-28.88%

Growth (annualized)

Metric	AGEN	BNTC
Revenue CAGR (5Y)	14.13%	N/A
Total return CAGR (5Y)	-40.10%	-31.08%

Frequently asked

Is AGEN or BNTC more profitable?: AGEN runs the higher net margin — AGEN at 69.34% versus BNTC at 0.00%.
How have AGEN and BNTC total returns compared?: Over the past 10 years, AGEN delivered -24.61% and BNTC delivered -30.49% annualized total return. Past performance doesn't predict future results.

Go deeper

Full AGEN analysis Full BNTC analysis Interactive comparison tool

Dig into the metrics

Agenus P/E ratio Agenus ROE Benitec Biopharma ROE Agenus operating margin Benitec Biopharma operating margin Agenus revenue growth Benitec Biopharma revenue growth Agenus free cash flow Benitec Biopharma free cash flow

Agenus & Benitec Biopharma appear in these rankings

Lowest P/E Ratio Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.