Is AGEN or ARTV more profitable?

AGEN runs the higher net margin — AGEN at 69.34% versus ARTV at 0.00%.

Agenus Inc. (AGEN) vs Artiva Biotherapeutics, Inc. (ARTV)

A side-by-side comparison of Agenus Inc. and Artiva Biotherapeutics, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

AGEN

Agenus Inc.

$343M

$8.23HealthcareDelayed quote: Oct 6, 2026, 10:10 AM EDT

ARTV

Artiva Biotherapeutics, Inc.

$340M

$6.96HealthcareDelayed quote: Oct 6, 2026, 10:10 AM EDT

Total return — AGEN vs ARTV

growth of $100 · dividends reinvested · last 2y

AGEN -44.0% (-25.2%/yr)ARTV -40.6% (-22.9%/yr)ARTV compounded faster over this window

AGEN ARTV

AGEN vs ARTV: by the numbers

•AGEN is the larger company ($343M vs $340M market cap).
•AGEN is profitable (69.34% net margin) while ARTV runs a net loss (0.00%).

Metrics side by side

Valuation

Metric	AGEN	ARTV
P/E ratio	3.11	N/A
Forward P/E	30.77	N/A
P/S ratio	2.58	N/A
P/B ratio	N/A	0.98
EV / EBITDA	8.91	N/A

Profitability

Metric	AGEN	ARTV
Gross margin	29.63%	0.00%
Operating margin	-18.00%	0.00%
Net margin	69.34%	0.00%
ROE	N/A	-26.14%
ROIC	N/A	-27.16%

Growth (annualized)

Metric	AGEN	ARTV
Revenue CAGR (5Y)	14.13%	N/A
Total return CAGR (5Y)	-40.10%	N/A

Frequently asked

Is AGEN or ARTV more profitable?: AGEN runs the higher net margin — AGEN at 69.34% versus ARTV at 0.00%.

Go deeper

Full AGEN analysis Full ARTV analysis Interactive comparison tool

Dig into the metrics

Agenus P/E ratio Agenus ROE Artiva Biotherapeutics ROE Agenus operating margin Artiva Biotherapeutics operating margin Agenus revenue growth Artiva Biotherapeutics revenue growth Agenus free cash flow Artiva Biotherapeutics free cash flow

Agenus & Artiva Biotherapeutics appear in these rankings

Lowest P/E Ratio Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.