Actuate Therapeutics Inc (ACTU) vs Aytu BioPharma, Inc. (AYTU)
A side-by-side comparison of Actuate Therapeutics Inc and Aytu BioPharma, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
ACTU
Actuate Therapeutics Inc
$0.87HealthcareDelayed quote: Oct 5, 2026, 4:00 PM EDT
AYTU
Aytu BioPharma, Inc.
$2.04HealthcareDelayed quote: Oct 5, 2026, 4:00 PM EDT
Total return — ACTU vs AYTU
growth of $100 · dividends reinvested · last 2yACTU -89.8% (-68.1%/yr)AYTU -14.1% (-7.3%/yr)AYTU compounded faster over this window
Log scale — wide-divergence pair
ACTU AYTU
ACTU vs AYTU: by the numbers
- •AYTU is the larger company ($22M vs $21M market cap).
- •Both run net losses; ACTU's is the smaller (0.00% vs -24.76% net margin).
Metrics side by side
Valuation
| Metric | ACTU | AYTU |
|---|---|---|
| P/S ratio | N/A | 0.38 |
| P/B ratio | 21.16 | 0.62 |
| FCF yield | N/A | 14.85% |
Profitability
| Metric | ACTU | AYTU |
|---|---|---|
| Gross margin | 0.00% | 63.95% |
| Operating margin | 0.00% | -14.44% |
| Net margin | 0.00% | -24.76% |
| ROE | -2067.81% | -40.40% |
| ROIC | -1489.99% | -14.21% |
Growth (annualized)
| Metric | ACTU | AYTU |
|---|---|---|
| Revenue CAGR (5Y) | N/A | -2.59% |
| Total return CAGR (5Y) | N/A | -48.14% |
Go deeper
Dig into the metrics
Actuate Therapeutics ROEAytu BioPharma ROEActuate Therapeutics operating marginAytu BioPharma operating marginActuate Therapeutics revenue growthAytu BioPharma revenue growthActuate Therapeutics free cash flowAytu BioPharma free cash flow
Actuate Therapeutics & Aytu BioPharma appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.