Aclaris Therapeutics, Inc. (ACRS) vs ProKidney Corp. (PROK)

A side-by-side comparison of Aclaris Therapeutics, Inc. and ProKidney Corp. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

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Total return — ACRS vs PROK

growth of $100 · dividends reinvested · last 5y
ACRS -75.7% (-24.6%/yr)PROK -84.4% (-31.0%/yr)ACRS compounded faster over this window
050100Start $10020222023202420252026$24$16
ACRS PROK

ACRS vs PROK: by the numbers

  • •ACRS is the larger company ($549M vs $536M market cap).
  • •Both run net losses; ACRS's is the smaller (-921.50% vs -10599.76% net margin).

Metrics side by side

Valuation

MetricACRSPROK
P/S ratio66.84655.65
P/B ratio4.41N/A

Profitability

MetricACRSPROK
Gross margin73.28%100.00%
Operating margin-975.91%-18477.83%
Net margin-921.50%-10599.76%
ROE-60.79%N/A
ROIC-56.99%-78.31%

Growth (annualized)

MetricACRSPROK
Revenue CAGR (5Y)4.39%N/A
Total return CAGR (5Y)-24.23%-30.65%

Frequently asked

How have ACRS and PROK total returns compared?
Over the past 5 years, ACRS delivered -24.23% and PROK delivered -30.65% annualized total return. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.