Aclaris Therapeutics, Inc. (ACRS) vs Monopar Therapeutics Inc. (MNPR)

A side-by-side comparison of Aclaris Therapeutics, Inc. and Monopar Therapeutics Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

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Total return — ACRS vs MNPR

growth of $100 · dividends reinvested · last 7y
ACRS +135.9% (+13.0%/yr)MNPR -40.9% (-7.2%/yr)ACRS compounded faster over this window
05001k2kStart $100202120232025$236$59
ACRS MNPR

ACRS vs MNPR: by the numbers

  • •ACRS is the larger company ($564M vs $524M market cap).
  • •Both run net losses; MNPR's is the smaller (0.00% vs -921.50% net margin).

Metrics side by side

Valuation

MetricACRSMNPR
P/S ratio68.57N/A
P/B ratio4.524.00

Profitability

MetricACRSMNPR
Gross margin73.28%0.00%
Operating margin-975.91%0.00%
Net margin-921.50%0.00%
ROE-60.79%-13.64%
ROIC-56.99%-16.89%

Growth (annualized)

MetricACRSMNPR
Revenue CAGR (5Y)4.39%N/A
Total return CAGR (5Y)-24.23%27.38%

Frequently asked

How have ACRS and MNPR total returns compared?
Over the past 5 years, ACRS delivered -24.23% and MNPR delivered 27.38% annualized total return. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.