AC Immune S.A. (ACIU) vs Nautilus Biotechnolgy, Inc. (NAUT)
A side-by-side comparison of AC Immune S.A. and Nautilus Biotechnolgy, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
ACIU
AC Immune S.A.
$2.56HealthcareDelayed quote: Oct 6, 2026, 12:45 PM EDT
NAUT
Nautilus Biotechnolgy, Inc.
$1.90HealthcareDelayed quote: Oct 6, 2026, 12:40 PM EDT
Total return — ACIU vs NAUT
growth of $100 · dividends reinvested · last 6yACIU -58.8% (-13.7%/yr)NAUT -82.1% (-24.9%/yr)ACIU compounded faster over this window
ACIU NAUT
ACIU vs NAUT: by the numbers
- •ACIU is the larger company ($260M vs $242M market cap).
- •Both run net losses; ACIU's is the smaller (-249.94% vs -29747.89% net margin).
Metrics side by side
Valuation
| Metric | ACIU | NAUT |
|---|---|---|
| P/S ratio | 11.98 | 1272.62 |
| P/B ratio | 5.98 | 1.84 |
Profitability
| Metric | ACIU | NAUT |
|---|---|---|
| Gross margin | 100.00% | 0.00% |
| Operating margin | -1927.32% | 0.00% |
| Net margin | -249.94% | -29747.89% |
| ROE | -124.67% | -43.11% |
| ROIC | -89.43% | -40.52% |
Growth (annualized)
| Metric | ACIU | NAUT |
|---|---|---|
| Revenue CAGR (5Y) | -23.70% | N/A |
| Total return CAGR (5Y) | -16.03% | -20.56% |
Frequently asked
- How have ACIU and NAUT total returns compared?
- Over the past 5 years, ACIU delivered -16.03% and NAUT delivered -20.56% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.