AC Immune S.A. (ACIU) vs Fulcrum Therapeutics, Inc. (FULC)

A side-by-side comparison of AC Immune S.A. and Fulcrum Therapeutics, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

Compare

Total return — ACIU vs FULC

growth of $100 · dividends reinvested · last 7y
ACIU -51.4% (-9.8%/yr)FULC -72.5% (-16.8%/yr)ACIU compounded faster over this window
050100150200Start $100202120232025$49$27
ACIU FULC

ACIU vs FULC: by the numbers

  • •FULC is the larger company ($283M vs $276M market cap).
  • •Both run net losses; FULC's is the smaller (0.00% vs -249.94% net margin).

Metrics side by side

Valuation

MetricACIUFULC
P/S ratio12.71N/A
P/B ratio6.340.91

Profitability

MetricACIUFULC
Gross margin100.00%0.00%
Operating margin-1927.32%0.00%
Net margin-249.94%0.00%
ROE-124.67%-27.36%
ROIC-89.43%-27.62%

Growth (annualized)

MetricACIUFULC
Revenue CAGR (5Y)-23.70%N/A
Total return CAGR (5Y)-16.03%-31.70%

Frequently asked

How have ACIU and FULC total returns compared?
Over the past 5 years, ACIU delivered -16.03% and FULC delivered -31.70% annualized total return. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.