Is ACHV or MDXG more profitable?

MDXG runs the higher net margin — ACHV at 0.00% versus MDXG at 1.76%.

How have ACHV and MDXG total returns compared?

Over the past 10 years, ACHV delivered -39.18% and MDXG delivered -6.46% annualized total return. Past performance doesn't predict future results.

Achieve Life Sciences, Inc. (ACHV) vs MiMedx Group, Inc. (MDXG)

A side-by-side comparison of Achieve Life Sciences, Inc. and MiMedx Group, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

ACHV

Achieve Life Sciences, Inc.

$731M

$7.13HealthcareDelayed quote: Oct 6, 2026, 11:00 AM EDT

MDXG

MiMedx Group, Inc.

$665M

$4.57HealthcareDelayed quote: Oct 6, 2026, 10:55 AM EDT

Total return — ACHV vs MDXG

growth of $100 · dividends reinvested · last 10y

ACHV -99.3% (-38.9%/yr)MDXG -48.5% (-6.4%/yr)MDXG compounded faster over this window

Log scale — wide-divergence pair

ACHV MDXG

ACHV vs MDXG: by the numbers

•ACHV is the larger company ($731M vs $665M market cap).
•MDXG is profitable (1.76% net margin) while ACHV runs a net loss (0.00%).

Metrics side by side

Valuation

Metric	ACHV	MDXG
P/E ratio	N/A	114.13
P/S ratio	N/A	1.87
P/B ratio	N/A	3.08
EV / EBITDA	N/A	26.02
FCF yield	N/A	6.10%

Profitability

Metric	ACHV	MDXG
Gross margin	0.00%	78.85%
Operating margin	0.00%	15.26%
Net margin	0.00%	1.76%
ROE	N/A	2.89%
ROIC	N/A	1.97%

Growth (annualized)

Metric	ACHV	MDXG
Revenue CAGR (5Y)	N/A	6.36%
Total return CAGR (5Y)	-4.33%	-4.94%

Frequently asked

Is ACHV or MDXG more profitable?: MDXG runs the higher net margin — ACHV at 0.00% versus MDXG at 1.76%.
How have ACHV and MDXG total returns compared?: Over the past 10 years, ACHV delivered -39.18% and MDXG delivered -6.46% annualized total return. Past performance doesn't predict future results.

Go deeper

Full ACHV analysis Full MDXG analysis Interactive comparison tool

Dig into the metrics

MiMedx P/E ratio Achieve Life Sciences ROE MiMedx ROE Achieve Life Sciences operating margin MiMedx operating margin Achieve Life Sciences revenue growth MiMedx revenue growth Achieve Life Sciences free cash flow MiMedx free cash flow

Achieve Life Sciences & MiMedx appear in these rankings

Highest FCF Yield Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.