Achieve Life Sciences, Inc. (ACHV) vs Lexicon Pharmaceuticals, Inc. (LXRX)
A side-by-side comparison of Achieve Life Sciences, Inc. and Lexicon Pharmaceuticals, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
ACHV
Achieve Life Sciences, Inc.
$6.93HealthcareDelayed quote: Oct 6, 2026, 10:30 AM EDT
LXRX
Lexicon Pharmaceuticals, Inc.
$1.73HealthcareDelayed quote: Oct 6, 2026, 10:25 AM EDT
Total return — ACHV vs LXRX
growth of $100 · dividends reinvested · last 10yACHV -99.3% (-38.9%/yr)LXRX -90.8% (-21.2%/yr)LXRX compounded faster over this window
Log scale — wide-divergence pair
ACHV LXRX
ACHV vs LXRX: by the numbers
- •LXRX is the larger company ($769M vs $711M market cap).
- •Both run net losses; ACHV's is the smaller (0.00% vs -147.38% net margin).
Metrics side by side
Valuation
| Metric | ACHV | LXRX |
|---|---|---|
| P/S ratio | N/A | 18.53 |
| P/B ratio | N/A | 4.40 |
Profitability
| Metric | ACHV | LXRX |
|---|---|---|
| Gross margin | 0.00% | 98.85% |
| Operating margin | 0.00% | -98.21% |
| Net margin | 0.00% | -147.38% |
| ROE | N/A | -35.02% |
| ROIC | N/A | -23.16% |
Growth (annualized)
| Metric | ACHV | LXRX |
|---|---|---|
| Revenue CAGR (5Y) | N/A | 42.36% |
| Total return CAGR (5Y) | -4.33% | -18.54% |
Frequently asked
- How have ACHV and LXRX total returns compared?
- Over the past 10 years, ACHV delivered -39.18% and LXRX delivered -21.03% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Achieve Life Sciences ROELexicon Pharmaceuticals ROEAchieve Life Sciences operating marginLexicon Pharmaceuticals operating marginAchieve Life Sciences revenue growthLexicon Pharmaceuticals revenue growthAchieve Life Sciences free cash flowLexicon Pharmaceuticals free cash flow
Achieve Life Sciences & Lexicon Pharmaceuticals appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.