Achieve Life Sciences, Inc. (ACHV) vs Avalo Therapeutics, Inc. (AVTX)

A side-by-side comparison of Achieve Life Sciences, Inc. and Avalo Therapeutics, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

Compare

Total return — ACHV vs AVTX

growth of $100 · dividends reinvested · last 10y
ACHV -99.3% (-38.9%/yr)AVTX -99.9% (-48.7%/yr)ACHV compounded faster over this window
Log scale — wide-divergence pair
001101001kStart $10020182020202220242026$1$0
ACHV AVTX

ACHV vs AVTX: by the numbers

  • •AVTX is the larger company ($767M vs $720M market cap).
  • •Both run net losses; ACHV's is the smaller (0.00% vs -170055.93% net margin).

Metrics side by side

Valuation

MetricACHVAVTX
P/S ratioN/A13007.76
P/B ratioN/A1.71

Profitability

MetricACHVAVTX
Gross margin0.00%100.00%
Operating margin0.00%-123601.69%
Net margin0.00%-170055.93%
ROEN/A-22.36%
ROICN/A-19.45%

Growth (annualized)

MetricACHVAVTX
Revenue CAGR (5Y)N/A-60.88%
Total return CAGR (5Y)-4.33%-70.04%

Frequently asked

How have ACHV and AVTX total returns compared?
Over the past 10 years, ACHV delivered -39.18% and AVTX delivered -48.70% annualized total return. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.