Achieve Life Sciences, Inc. (ACHV) vs Annexon, Inc. (ANNX)
A side-by-side comparison of Achieve Life Sciences, Inc. and Annexon, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
ACHV
Achieve Life Sciences, Inc.
$7.20HealthcareDelayed quote: Oct 6, 2026, 12:00 PM EDT
ANNX
Annexon, Inc.
$4.18HealthcareDelayed quote: Oct 6, 2026, 11:55 AM EDT
Total return — ACHV vs ANNX
growth of $100 · dividends reinvested · last 6yACHV -18.4% (-3.3%/yr)ANNX -76.4% (-21.4%/yr)ACHV compounded faster over this window
ACHV ANNX
ACHV vs ANNX: by the numbers
- •ACHV is the larger company ($739M vs $684M market cap).
Metrics side by side
Valuation
| Metric | ACHV | ANNX |
|---|---|---|
| P/B ratio | N/A | 3.68 |
Profitability
| Metric | ACHV | ANNX |
|---|---|---|
| Gross margin | 0.00% | 0.00% |
| Operating margin | 0.00% | 0.00% |
| Net margin | 0.00% | 0.00% |
| ROE | N/A | -108.93% |
| ROIC | N/A | -101.43% |
Growth (annualized)
| Metric | ACHV | ANNX |
|---|---|---|
| Total return CAGR (5Y) | -4.33% | -26.29% |
Frequently asked
- How have ACHV and ANNX total returns compared?
- Over the past 5 years, ACHV delivered -4.33% and ANNX delivered -26.29% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.