Arbutus Biopharma Corp (ABUS) vs SI-BONE, Inc. (SIBN)
A side-by-side comparison of Arbutus Biopharma Corp and SI-BONE, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
ABUS
Arbutus Biopharma Corp
$4.48HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT
SIBN
SI-BONE, Inc.
$19.53HealthcareDelayed quote: Oct 6, 2026, 3:55 PM EDT
Total return — ABUS vs SIBN
growth of $100 · dividends reinvested · last 8yABUS +8.4% (+1.0%/yr)SIBN -1.2% (-0.2%/yr)ABUS compounded faster over this window
ABUS SIBN
ABUS vs SIBN: by the numbers
- •ABUS is the larger company ($885M vs $866M market cap).
- •ABUS is profitable (84.23% net margin) while SIBN runs a net loss (-6.85%).
- •ABUS grew revenue faster over the past five years (85.17% vs 20.20% CAGR).
Metrics side by side
Valuation
| Metric | ABUS | SIBN |
|---|---|---|
| P/E ratio | 5.74 | N/A |
| Forward P/E | 6.05 | N/A |
| P/S ratio | 4.87 | 4.05 |
| P/B ratio | 3.42 | 4.75 |
| EV / EBITDA | 5.90 | N/A |
Profitability
| Metric | ABUS | SIBN |
|---|---|---|
| Gross margin | 99.98% | 79.53% |
| Operating margin | -192.08% | -8.31% |
| Net margin | 84.23% | -6.85% |
| ROE | 59.16% | -8.03% |
| ROIC | 54.39% | -7.88% |
Growth (annualized)
| Metric | ABUS | SIBN |
|---|---|---|
| Revenue CAGR (5Y) | 85.17% | 20.20% |
| Total return CAGR (5Y) | 2.19% | -1.46% |
Frequently asked
- Which has grown faster, ABUS or SIBN?
- Over the past five years, ABUS grew revenue faster — ABUS at a 85.17% CAGR versus SIBN at 20.20%.
- Is ABUS or SIBN more profitable?
- ABUS runs the higher net margin — ABUS at 84.23% versus SIBN at -6.85%.
- How have ABUS and SIBN total returns compared?
- Over the past 5 years, ABUS delivered 2.19% and SIBN delivered -1.46% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Arbutus Biopharma P/E ratioArbutus Biopharma ROESI-BONE ROEArbutus Biopharma operating marginSI-BONE operating marginArbutus Biopharma revenue growthSI-BONE revenue growthArbutus Biopharma free cash flowSI-BONE free cash flow
Arbutus Biopharma & SI-BONE appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.