Pfizer Inc. (PFE) vs QUALCOMM Incorporated (QCOM)

A side-by-side comparison of Pfizer Inc. and QUALCOMM Incorporated across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of September 10, 2026. Differences are shown without an overall score or investment verdict.

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Different business models: PFE is classified in Healthcare; QCOM is classified in Technology. Margin, capital intensity, and valuation differences should be interpreted in that sector context.

Total returnPFE vs QCOM

growth of $100 · dividends reinvested · last 10y
PFE +37.3% (+3.2%/yr)QCOM +266.6% (+13.9%/yr)QCOM compounded faster over this window
100200300400500Start $10020182020202220242026$137$367
PFE QCOM

PFE vs QCOM: by the numbers

  • QCOM is the larger company ($191.07B vs $157.99B market cap).
  • QCOM trades at the lower trailing earnings multiple (20.77 vs 36.63 P/E), one valuation lens rather than an overall verdict.
  • QCOM converts more revenue to profit (21.01% vs 6.81% net margin).
  • PFE pays the higher dividend yield (6.19% vs 2.05%).

Metrics side by side

Valuation

MetricPFEQCOM
P/E ratio36.6320.77
Forward P/E9.3217.26
P/S ratio2.484.34
P/B ratio1.856.91
EV / EBITDA10.1517.11
FCF yield6.95%5.45%

Profitability

MetricPFEQCOM
Gross margin71.32%54.23%
Operating margin25.08%23.19%
Net margin6.81%21.01%
ROE5.09%33.48%
ROIC9.33%17.42%

Dividends

MetricPFEQCOM
Dividend yield6.19%2.05%
Payout ratio227.27%41.32%

Growth (annualized)

MetricPFEQCOM
Revenue CAGR (5Y)6.29%6.23%
EPS CAGR (5Y)-3.78%2.02%
FCF CAGR (5Y)-3.11%2.09%
Total return CAGR (5Y)-4.68%6.80%

Frequently asked

Which has the lower trailing P/E, PFE or QCOM?
QCOM has the lower trailing P/E: PFE trades at 36.63 and QCOM at 20.77. P/E is one valuation measure and does not by itself establish which business is cheaper.
Does PFE or QCOM pay a bigger dividend?
PFE yields 6.19% and QCOM yields 2.05% based on trailing dividends and the latest price.
Is PFE or QCOM more profitable?
QCOM runs the higher net margin — PFE at 6.81% versus QCOM at 21.01%.
How have PFE and QCOM total returns compared?
Over the past 10 years, PFE delivered 3.17% and QCOM delivered 14.33% annualized total return. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified September 10, 2026.