Eli Lilly and Company (LLY) vs Pfizer Inc. (PFE)
A side-by-side comparison of Eli Lilly and Company and Pfizer Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of September 11, 2026. Differences are shown without an overall score or investment verdict.
LLY
Eli Lilly and Company
$1,115.25HealthcareDelayed quote: Sep 11, 2026, 3:59 PM EDT
PFE
Pfizer Inc.
$27.72HealthcareDelayed quote: Sep 11, 2026, 4:01 PM EDT
Total return — LLY vs PFE
growth of $100 · dividends reinvested · last 10yLLY +1620.8% (+32.9%/yr)PFE +37.3% (+3.2%/yr)LLY compounded faster over this window
Log scale — wide-divergence pair
LLY PFE
LLY vs PFE: by the numbers
- •LLY is the larger company ($1.05T vs $157.99B market cap).
- •PFE trades at the lower trailing earnings multiple (36.63 vs 37.42 P/E), one valuation lens rather than an overall verdict.
- •LLY converts more revenue to profit (33.53% vs 6.81% net margin).
- •LLY grew revenue faster over the past five years (24.42% vs 6.29% CAGR).
- •PFE pays the higher dividend yield (6.19% vs 0.60%).
Metrics side by side
Valuation
| Metric | LLY | PFE |
|---|---|---|
| P/E ratio | 37.42 | 36.63 |
| Forward P/E | 30.64 | 9.32 |
| P/S ratio | 13.18 | 2.48 |
| P/B ratio | 31.00 | 1.85 |
| EV / EBITDA | 29.91 | 10.15 |
| FCF yield | 1.91% | 6.95% |
Profitability
| Metric | LLY | PFE |
|---|---|---|
| Gross margin | 84.01% | 71.32% |
| Operating margin | 43.92% | 25.08% |
| Net margin | 33.53% | 6.81% |
| ROE | 78.84% | 5.09% |
| ROIC | 27.38% | 9.33% |
Dividends
| Metric | LLY | PFE |
|---|---|---|
| Dividend yield | 0.60% | 6.19% |
| Payout ratio | 22.45% | 227.27% |
Growth (annualized)
| Metric | LLY | PFE |
|---|---|---|
| Revenue CAGR (5Y) | 24.42% | 6.29% |
| EPS CAGR (5Y) | 28.88% | -3.78% |
| FCF CAGR (5Y) | 32.91% | -3.11% |
| Total return CAGR (5Y) | 37.46% | -4.68% |
Frequently asked
- Which has the lower trailing P/E, LLY or PFE?
- PFE has the lower trailing P/E: LLY trades at 37.42 and PFE at 36.63. P/E is one valuation measure and does not by itself establish which business is cheaper.
- Which has grown faster, LLY or PFE?
- Over the past five years, LLY grew revenue faster — LLY at a 24.42% CAGR versus PFE at 6.29%.
- Does LLY or PFE pay a bigger dividend?
- LLY yields 0.60% and PFE yields 6.19% based on trailing dividends and the latest price.
- Is LLY or PFE more profitable?
- LLY runs the higher net margin — LLY at 33.53% versus PFE at 6.81%.
- How have LLY and PFE total returns compared?
- Over the past 10 years, LLY delivered 32.58% and PFE delivered 3.17% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Eli Lilly P/E ratioPfizer P/E ratioEli Lilly dividend yieldPfizer dividend yieldEli Lilly ROEPfizer ROEEli Lilly operating marginPfizer operating marginEli Lilly revenue growthPfizer revenue growthEli Lilly free cash flowPfizer free cash flow
Eli Lilly & Pfizer appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified September 11, 2026.