Eli Lilly and Company (LLY) vs Pfizer Inc. (PFE)

A side-by-side comparison of Eli Lilly and Company and Pfizer Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of September 11, 2026. Differences are shown without an overall score or investment verdict.

Compare

Total returnLLY vs PFE

growth of $100 · dividends reinvested · last 10y
LLY +1620.8% (+32.9%/yr)PFE +37.3% (+3.2%/yr)LLY compounded faster over this window
Log scale — wide-divergence pair
101001k10kStart $10020182020202220242026$1,721$137
LLY PFE

LLY vs PFE: by the numbers

  • LLY is the larger company ($1.05T vs $157.99B market cap).
  • PFE trades at the lower trailing earnings multiple (36.63 vs 37.42 P/E), one valuation lens rather than an overall verdict.
  • LLY converts more revenue to profit (33.53% vs 6.81% net margin).
  • LLY grew revenue faster over the past five years (24.42% vs 6.29% CAGR).
  • PFE pays the higher dividend yield (6.19% vs 0.60%).

Metrics side by side

Valuation

MetricLLYPFE
P/E ratio37.4236.63
Forward P/E30.649.32
P/S ratio13.182.48
P/B ratio31.001.85
EV / EBITDA29.9110.15
FCF yield1.91%6.95%

Profitability

MetricLLYPFE
Gross margin84.01%71.32%
Operating margin43.92%25.08%
Net margin33.53%6.81%
ROE78.84%5.09%
ROIC27.38%9.33%

Dividends

MetricLLYPFE
Dividend yield0.60%6.19%
Payout ratio22.45%227.27%

Growth (annualized)

MetricLLYPFE
Revenue CAGR (5Y)24.42%6.29%
EPS CAGR (5Y)28.88%-3.78%
FCF CAGR (5Y)32.91%-3.11%
Total return CAGR (5Y)37.46%-4.68%

Frequently asked

Which has the lower trailing P/E, LLY or PFE?
PFE has the lower trailing P/E: LLY trades at 37.42 and PFE at 36.63. P/E is one valuation measure and does not by itself establish which business is cheaper.
Which has grown faster, LLY or PFE?
Over the past five years, LLY grew revenue faster — LLY at a 24.42% CAGR versus PFE at 6.29%.
Does LLY or PFE pay a bigger dividend?
LLY yields 0.60% and PFE yields 6.19% based on trailing dividends and the latest price.
Is LLY or PFE more profitable?
LLY runs the higher net margin — LLY at 33.53% versus PFE at 6.81%.
How have LLY and PFE total returns compared?
Over the past 10 years, LLY delivered 32.58% and PFE delivered 3.17% annualized total return. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified September 11, 2026.