Henry Schein, Inc. (HSIC) vs 23andMe Holding Co. (ME)
HSIC leads on 6 of 9 compared metrics.
A side-by-side comparison of Henry Schein, Inc. and 23andMe Holding Co. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of July 9, 2026. The ● marks the stronger figure on each row (cheaper multiple, higher margin/return).
Total return — HSIC vs ME
growth of $100 · last 5yHSIC +14.3%ME -99.7%HSIC compounded faster
Log scale — wide-divergence pair
HSIC ME
HSIC vs ME: by the numbers
- •HSIC is the larger company ($9.55B vs $15M market cap).
- •HSIC is profitable (2.95% net margin) while ME runs a net loss (-134.54%).
- •HSIC grew revenue faster over the past five years (4.74% vs -9.07% CAGR).
Which is better, HSIC or ME?
Metric tally: HSIC 6 · ME 3It depends on what you're optimizing for:
GrowthHSIC(faster 5Y revenue CAGR)
QualityHSIC(higher ROIC)
Metrics side by side
Valuation
| Metric | HSIC | ME |
|---|---|---|
| P/E ratio | 25.14 | — |
| Forward P/E | 15.56 | — |
| P/S ratio | 0.72 | 0.10● |
| P/B ratio | 2.96 | 0.51● |
| PEG ratio | 3.23 | — |
| EV / EBITDA | 12.59 | — |
| FCF yield | 4.46% | — |
Profitability
| Metric | HSIC | ME |
|---|---|---|
| Gross margin | 29.69% | 53.33%● |
| Operating margin | 5.60%● | -126.72% |
| Net margin | 2.95%● | -134.54% |
| ROE | 12.09%● | -721.75% |
| ROIC | 6.58%● | -553.10% |
Growth (annualized)
| Metric | HSIC | ME |
|---|---|---|
| Revenue CAGR (5Y) | 4.74%● | -9.07% |
| EPS CAGR (5Y) | -0.74% | — |
| FCF CAGR (5Y) | -4.53% | — |
| Total return CAGR (5Y) | 1.89%● | -68.93% |
Frequently asked
- Which is better, HSIC or ME?
- It depends on your goal. growth: HSIC (faster 5Y revenue CAGR); quality: HSIC (higher ROIC). Across all compared metrics, HSIC leads 6 to 3.
- Which has grown faster, HSIC or ME?
- Over the past five years, HSIC grew revenue faster — HSIC at a 4.74% CAGR versus ME at -9.07%.
- Is HSIC or ME more profitable?
- HSIC runs the higher net margin — HSIC at 2.95% versus ME at -134.54%.
- Which has been the better investment, HSIC or ME?
- Over the past 5-year, HSIC delivered the higher annualized total return — HSIC at 1.62% versus ME at -68.93%. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Henry Schein P/E ratio23andMe P/E ratioHenry Schein dividend yield23andMe dividend yieldHenry Schein ROE23andMe ROEHenry Schein operating margin23andMe operating marginHenry Schein revenue growth23andMe revenue growthHenry Schein free cash flow23andMe free cash flow
Henry Schein & 23andMe appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified July 9, 2026.