Henry Schein, Inc. (HSIC) vs 23andMe Holding Co. (ME)

HSIC leads on 6 of 9 compared metrics.

A side-by-side comparison of Henry Schein, Inc. and 23andMe Holding Co. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of July 9, 2026. The ● marks the stronger figure on each row (cheaper multiple, higher margin/return).

Compare

Total return — HSIC vs ME

growth of $100 · last 5y
HSIC +14.3%ME -99.7%HSIC compounded faster
Log scale — wide-divergence pair
01101001kStart $100202120222023202420252026$114$0
HSIC ME

HSIC vs ME: by the numbers

  • HSIC is the larger company ($9.55B vs $15M market cap).
  • HSIC is profitable (2.95% net margin) while ME runs a net loss (-134.54%).
  • HSIC grew revenue faster over the past five years (4.74% vs -9.07% CAGR).

Which is better, HSIC or ME?

Metric tally: HSIC 6 · ME 3

It depends on what you're optimizing for:

GrowthHSIC(faster 5Y revenue CAGR)
QualityHSIC(higher ROIC)

Metrics side by side

Valuation

MetricHSICME
P/E ratio25.14
Forward P/E15.56
P/S ratio0.720.10
P/B ratio2.960.51
PEG ratio3.23
EV / EBITDA12.59
FCF yield4.46%

Profitability

MetricHSICME
Gross margin29.69%53.33%
Operating margin5.60%-126.72%
Net margin2.95%-134.54%
ROE12.09%-721.75%
ROIC6.58%-553.10%

Growth (annualized)

MetricHSICME
Revenue CAGR (5Y)4.74%-9.07%
EPS CAGR (5Y)-0.74%
FCF CAGR (5Y)-4.53%
Total return CAGR (5Y)1.89%-68.93%

Frequently asked

Which is better, HSIC or ME?
It depends on your goal. growth: HSIC (faster 5Y revenue CAGR); quality: HSIC (higher ROIC). Across all compared metrics, HSIC leads 6 to 3.
Which has grown faster, HSIC or ME?
Over the past five years, HSIC grew revenue faster — HSIC at a 4.74% CAGR versus ME at -9.07%.
Is HSIC or ME more profitable?
HSIC runs the higher net margin — HSIC at 2.95% versus ME at -134.54%.
Which has been the better investment, HSIC or ME?
Over the past 5-year, HSIC delivered the higher annualized total return — HSIC at 1.62% versus ME at -68.93%. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified July 9, 2026.